Study | Population | N | HSV-2 Ascertainment | Results | ||||
---|---|---|---|---|---|---|---|---|
Outcome | HSV2 positive | HSV2 negative | Difference | Effectb | ||||
Barnabas 2011 | HIV seroconverters, Americas | 87 | Serology: Western Blot | Initiation of HAART | NR | NR | aHR = 1.3c, (95% CI = 0.5, 3.2) | ↔ |
Crum-Cianflone 2006 | USA | 367 | Serology: Focus | Time from HIV diagnosis to initiation of any ARTd | 18 months | 9 months | p = 0.10 | ↔ |
(range = 1,156) | (range = 1,96) | |||||||
271 | Proportion with CD4≤350 or 18% at 1 year of follow-upe | 62/144 = 43% | 66/127 = 52% | OR = 0.70, p = 0.15 | ↔ | |||
221 | Proportion with CD4≤350 or 18% at 3 years of follow-upe | 84/118 = 71% | 75/103 = 73% | OR = 0.92, p = 0.88 | ↔ | |||
Roxby 2011 | Postpartum women, Kenya | 296 | Serology: Focus | CD4≤200 | 50/254 = 20% | 7/42 = 17% | aHR = 1.16f, (95% CI = 0.52,2.56), p = 0.72 | ↔ |
First OI | 43/254 = 17% | 2/42 = 5% | aHR = 3.83f, (95% CI = 0.93,15.83), p = 0.06 | Faster? | ||||
Death | 17/254 = 7% | 2/42 = 5% | aHR = 1.33f, (95% CI = 0.32,6.05), p = 0.66 | ↔ | ||||
Suligoi 2001 | Italy | 380 | Serology: Pockit | AIDS | NR | NR | HR = 1.68, (95% CI = 1.19,2.37), Adjustedg HR = 1.13, (95% CI = 0.76, 1.70) | Faster? |