Table 1 Sources of hepatitis E virus inocula used to infect the cynomolgus monkeys
Source | Inocula | Anti-HEV serology | HEV RT-PCR/real-time PCR | Genotype | Age of monkey (years) | Animal ID |
|---|---|---|---|---|---|---|
Swine | Pooled faeces (3.0Â ml) | _ | HEV RNA+/105 copies/ml | 3 | 15 | I3 |
18 | Q11 | |||||
2 | X15 | |||||
Swine | Pooled faeces (3.0Â ml) | _ | HEV RNA+/106 copies/ml | 3 | 11 | O1 |
17 | G3 | |||||
19 | F3 | |||||
Child, female, 3 months old (FALF*) | Serum and faeces (1.0 ml) | Undetectable | Undetectable/103 copies/ml | 3 | 7 | R7 |
Adult, male, 30 years old (AH**) | Serum (1.0 ml) | IgG+/IgM+ | HEV RNA+/106 copies/ml | 3 | 14 | J3 |
- | 10% Phosphate-buffered saline (1.0Â ml) | _ | Undetectable | _ | 16 | I2 |
18 | Q12 |