High incidence of septic shock caused by Streptococcus pneumoniae serotype 3 - a retrospective epidemiological study

Table 2 Characteristics of patients with IPD grouped according to invasive potential of the infecting pneumococcal serotype

Invasive disease potentialª (no)	Septic shock (%)	28 day mortality (%)	Admitted to the ICU (%)	Any co-morbidity (%)	Two or more co-morbidities per patient (%)	Median age (years; range)
High ^b ( n = 85)	7 (8%)	6 (7%)	12 (14%)	41 (48%)	19 (22%)	62 (19–95)
Intermediate ^c ( n = 192)	18 (9%)	25 (13%)	29 (15%)	117 (61%)	52 (27%)	68 (20–97)
Low ^d ( n = 169)	17 (10%)	24 (14%)	24 (14%)	133 (79%)	74 (44%)	72 (23–101)
p -value ^e	p=0.911	p=0.293	p=0.984	p <0.001	p <0.001	p <0.001

ªSerogroups divided into groups depending of invasive potential according to Brueggeman et al.[3]. Sixty-seven IPD cases were excluded since the serotype was not included in this classification.
^bHigh invasive disease potential includes serotypes in serogroups 1, 5, and 7.
^cIntermediate invasive disease potential includes serotypes in serogroups 4, 9, 14 and 18.
^dLow invasive disease potential includes serotypes in serogroups 3, 6, 8, 15, 19, 23, and 33.
^eUnivariate p-value for differences among the groups (high, intermediate and low invasive potential).

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