Table 3 Demographic data of patients with meningitis due to Enterovirus
Phase 1 | Phase 2 | P value | ||||
|---|---|---|---|---|---|---|
N = 35 | % | N = 71 | % | |||
Gender | Female | 14 | 40 | 19 | 26.8 | 0.16 |
Male | 21 | 60 | 52 | 73.2 | ||
Presence of any comorbidity | 8 | 23.5 | 5 | 7 | 0.02 | |
Headache | 29 | 90.6 | 63 | 92.6 | 0.70 | |
Nausea and vomiting | 30 | 66.7 | 57 | 70.4 | 0.66 | |
Fever > 37.7°C | 26 | 81.3 | 50 | 73.5 | 0.39 | |
Stiff neck | 13 | 40.6 | 32 | 47.1 | 0.54 | |
Predominant cellularity in 1st CSF sample | Neutrophilic | 10 | 28.6 | 29 | 40.8 | 0.21 |
Lymphomonocytic | 25 | 71.4 | 42 | 59.2 | ||
Predominant cellularity in 2nd CSF sample | Neutrophilic | 0 | 0 | 0 | 0 | *** |
Lymphomonocytic | 4 | 100 | 3 | 100 | ||
Use of antibacterials to treat meningitis | 6 | 17.1 | 18 | 25.4 | 0.34 | |
Underwent imaging exam (brain) | 13 | 37.1 | 29 | 40.8 | 0.71 | |
Phase 1 | Phase 2 | P value | ||||
Mean | SD | Mean | SD | |||
Age (years) | 12.5 | 11.7 | 12.5 | 12.8 | 0.98 | |
Length of hospital stay (days) | 2.4 | 2.3 | 1.9 | 2.4 | 0.25 | |
Time from symptom onset to admission | 2.34 | 2.55 | 1.58 | 1.28 | 0.10 | |
Leukocytes in 1st CSF sample (n/mm3) | 254.9 | 262.5 | 184.5 | 208.5 | 0.13 | |
Neutrophils in 1st CSF sample (%) | 38.7 | 27.3 | 43.9 | 27.8 | 0.36 | |
Lymphocytes in 1st CSF sample (%) | 40.2 | 23.1 | 37.5 | 24.6 | 0.58 | |