|
Gender
|
Female
|
25
|
52.1
|
31
|
36.9
|
0.09
|
|
Male
|
23
|
47.9
|
53
|
63.1
|
|
Meningitis
|
Herpes
|
13
|
27.1
|
13
|
15.5
|
0.10
|
|
Enterovirus
|
35
|
72.9
|
71
|
84.5
|
|
Presence of any comorbidity
| |
11
|
22.9
|
12
|
14.5
|
0.19
|
|
Headache
| |
42
|
87.5
|
75
|
92.6
|
0.99
|
|
Nausea and vomiting
| |
30
|
62.5
|
57
|
70.4
|
0.66
|
|
Fever (T > 37.7°C)
| |
35
|
72.9
|
55
|
67.9
|
0.24
|
|
Stiff neck
| |
19
|
39.6
|
40
|
49.4
|
0.44
|
|
Predominant cellularity in 1st CSF sample
|
Neutrophilic
|
11
|
22.9
|
29
|
34.9
|
0.15
|
|
Lymphomonocytic
|
37
|
77.1
|
54
|
65.1
|
|
Result of NAAT for Enterovirus
|
Negative
|
12
|
25.5
|
13
|
15.5
|
0.02
|
|
Positive
|
35
|
74.5
|
71
|
84.5
|
|
Result of NAAT for Herpes simplex
|
Negative
|
29
|
60.4
|
64
|
76.2
|
0.18
|
|
Positive for HSV type I
|
1
|
2.1
|
0
|
0
|
|
Positive for HSV type II
|
12
|
25
|
13
|
15.5
|
|
Predominant cellularity in 2nd CSF sample
|
Neutrophilic
|
0
|
0
|
0
|
0
|
***
|
|
Lymphomonocytic
|
7
|
100
|
7
|
100
|
|
Use of antibacterials to treat meningitis
| |
7
|
14.6
|
19
|
22.6
|
0.264
|
|
Underwent imaging exam (brain)
| |
22
|
45.8
|
41
|
49.4
|
0.694
|
| | |
Phase 1
|
Phase 2
|
P value
|
| | |
Mean
|
SD
|
Mean
|
SD
| |
|
Age (years)
|
20.0
|
16.5
|
17.5
|
17.3
|
0.43
|
|
Length of hospital stay (days)
|
2.9
|
2.6
|
2.7
|
4.0
|
0.69
|
|
Time from symptom onset to admission
|
2.13
|
2.23
|
1.60
|
1.26
|
0.08
|
|
Leukocytes in 1st CSF sample (n/mm3)
|
262.9
|
259.6
|
205.2
|
217.7
|
0.17
|
|
Neutrophils in 1st CSF sample (%)
|
29.9
|
28.5
|
38.3
|
29.2
|
0.11
|
|
Lymphocytes in 1st CSF sample (%)
|
50.3
|
28.3
|
43.9
|
28.2
|
0.21
|
