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Table 2 Sample including Enterovirus and HSV 1/2

From: Improving the diagnosis of meningitis due to enterovirus and herpes simplex virus I and II in a tertiary care hospital

   Phase 1 Phase 2 P value
   n % n %  
Gender Female 25 52.1 31 36.9 0.09
Male 23 47.9 53 63.1
Meningitis Herpes 13 27.1 13 15.5 0.10
Enterovirus 35 72.9 71 84.5
Presence of any comorbidity   11 22.9 12 14.5 0.19
Headache   42 87.5 75 92.6 0.99
Nausea and vomiting   30 62.5 57 70.4 0.66
Fever (T > 37.7°C)   35 72.9 55 67.9 0.24
Stiff neck   19 39.6 40 49.4 0.44
Predominant cellularity in 1st CSF sample Neutrophilic 11 22.9 29 34.9 0.15
Lymphomonocytic 37 77.1 54 65.1
Result of NAAT for Enterovirus Negative 12 25.5 13 15.5 0.02
Positive 35 74.5 71 84.5
Result of NAAT for Herpes simplex Negative 29 60.4 64 76.2 0.18
Positive for HSV type I 1 2.1 0 0
Positive for HSV type II 12 25 13 15.5
Predominant cellularity in 2nd CSF sample Neutrophilic 0 0 0 0 ***
Lymphomonocytic 7 100 7 100
Use of antibacterials to treat meningitis   7 14.6 19 22.6 0.264
Underwent imaging exam (brain)   22 45.8 41 49.4 0.694
   Phase 1 Phase 2 P value
   Mean SD Mean SD  
Age (years) 20.0 16.5 17.5 17.3 0.43
Length of hospital stay (days) 2.9 2.6 2.7 4.0 0.69
Time from symptom onset to admission 2.13 2.23 1.60 1.26 0.08
Leukocytes in 1st CSF sample (n/mm3) 262.9 259.6 205.2 217.7 0.17
Neutrophils in 1st CSF sample (%) 29.9 28.5 38.3 29.2 0.11
Lymphocytes in 1st CSF sample (%) 50.3 28.3 43.9 28.2 0.21
  1. ***testing not possible.