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Table 2 rpoB mutations in M. tuberculosis from South Korea

From: Utility of the REBA MTB-rifa® assay for rapid detection of rifampicin resistant Mycobacterium Tuberculosis

Sequencing REBA MTB-Rifa® assay Sputum Isolates Total
533CTG-CCG 533CTG-CCG, ∆530-534 8 8 16
531TCG-TTG 531TCG-TTG, ∆530-534 59 115 174
531TCG-TGG ∆530-534 1 3 4
531TCG-TGC ∆530-534 1 1 2
531TCG-CAG ∆530-534 0 2 2
526CAC-TAC ∆524-529 4 14 18
526CAC-GAC ∆524-529 4 9 13
526CAC-CTC ∆524-529 2 4 6
526CAC-CCC ∆524-529 1 1 2
526CAC-CGC ∆524-529 1 2 3
526CAC-AAC ∆524-529 0 1 1
526CAC-TGC ∆524-529 0 3 3
526CAC-GGC ∆524-529 0 1 1
526CAC-TCC ∆524-529 0 1 1
522TCG-TGG ∆520-524 0 1 1
518AAC deletion ∆515-520 0 2 2
516GAC-GTC 516GAC-GTC, ∆515-520 6 18 24
516GAC-TAC ∆515-520 3 6 9
516GAC-AAC ∆515-520 0 1 1
513-514 CAA insertion ∆509-514 0 1 1
513-516 deletion ∆509-514, ∆515-520 1 1 2
514TTC-ATC ∆509-514 1 0 1
513CAA-AAA ∆509-514 1 3 4
513CAA-CTA ∆509-514 1 2 3
511CTG-CCG ∆509-514 0 3 3
511CTG-CCG, 516GAC-GGC ∆509-514, ∆515-520 1 0 1
510CAG-CAC, 511CTG-CCG ∆509-514 1 0 1
531TCG-TTG, 516GAC-TAC 531TCG-TTG, ∆530-534, ∆515-520 0 1 1
533CTG-CCG, 516GAC-GGC 533CTG-CCG, ∆530-534, ∆515-520 0 2 2
526CAC-AAC, 516GAC-AAC ∆524-529, ∆515-520 0 1 1
523GGG-GAG, 513CAA-CTA ∆520-524, ∆509-514 0 1 1
518AAC-CAC, 516GAC-GGC ∆515-520 0 1 1
516GAC-GGC, 515ATG-GTG ∆515-520 0 1 1
516GAC-GTC, 513CAA-GAA ∆515-520, ∆509-514 0 1 1
Total   96 211 307
  1. Bold texts are newly identified mutations in this study; ∆, missing wild type probe signal.