All-cause mortality | Cancer-specific mortality | ||||
---|---|---|---|---|---|
RH [95% CI] | p-value | RH [95% CI] | p-value | ||
Any NADC | |||||
Gender | Male | 1.69 [1.21, 2.36] | 0.002 | 1.59 [1.11, 2.26] | 0.01 |
Female | Ref. | - | Ref. | - | |
Mode of infection | Heterosexual | Ref. | - | Ref. | - |
MSM | 0.84 [0.63, 1.11] | 0.22 | 0.84 [0.62, 1.13] | 0.24 | |
IDU | 1.35 [0.98, 1.87] | 0.07 | 1.23 [0.87, 1.74] | 0.24 | |
Other/unknown | 0.78 [0.48, 1.26] | 0.30 | 0.72 [0.42, 1.22] | 0.22 | |
Ethnic group | White | Ref. | - | Ref. | - |
Non-white/other/not collected | 1.25 [0.99, 1.56] | 0.06 | 1.18 [0.93, 1.49] | 0.19 | |
Smoking status | Current smoker | 1.33 [0.88, 1.99] | 0.17 | 1.43 [0.92, 2.23] | 0.11 |
Ex-smoker | 1.79 [1.18, 2.70] | 0.006 | 1.88 [1.20, 2.94] | 0.006 | |
Non-smoker | Ref. | - | Ref. | - | |
Unknown | 1.60 [0.99, 2.59] | 0.05 | 1.69 [1.01, 2.83] | 0.05 | |
HBV status | Positive | 1.42 [0.96, 2.12] | 0.08 | 1.38 [0.90, 2.12] | 0.14 |
Negative | Ref. | Ref. | |||
Year of diagnosis | /later year | 0.93 [0.86, 0.99] | 0.04 | 0.91 [0.84, 0.98] | 0.01 |
CD4 count at diagnosis | /50 cells/mm3 higher | 0.95 [0.93, 0.98] | 0.0001 | 0.96 [0.94, 0.98] | 0.0007 |
Type of NADC | Lung cancer | 2.28 [1.75, 2.98] | 0.0001 | 2.43 [1.84, 3.21] | 0.0001 |
Anal cancer | 0.58 [0.36, 0.92] | 0.02 | 0.55 [0.33, 0.92] | 0.02 | |
Hodgkin’s lymphoma | 0.49 [0.32, 0.75] | 0.001 | 0.36 [0.21, 0.60] | 0.001 | |
Other | Ref. | - | Ref. | - | |
Lung cancer | |||||
HCV status | Positive | 1.88 [0.97, 3.66] | 0.06 | 2.02 [1.04, 3.95] | 0.04 |
Negative | Ref. | - | Ref. | - | |
Stage of disease | Disseminated | 5.22 [1.85, 14.76] | 0.002 | 4.84 [1.71, 13.74] | 0.003 |
Localised | Ref. | - | Ref. | - | |
Unknown | 5.95 [2.12, 16.74] | 0.0007 | 5.69 [2.02, 16.06] | 0.001 | |
Anal cancer | |||||
HCV status | Positive | 4.97 [1.55, 15.89] | 0.007 | 4.16 [1.18, 14.67] | 0.03 |
Negative | Ref. | - | Ref. | - | |
Previous NADC | 12.00 [2.98, 48.32] | 0.0005 | 10.17 [1.96, 52.73] | 0.006 | |
Stage of disease | Disseminated | 2.49 [0.73, 8.54] | 0.15 | 2.29 [0.65, 8.10] | 0.20 |
Localised | Ref. | - | Ref. | - | |
Unknown | 3.24 [0.94, 11.18] | 0.06 | 2.43 [0.66, 8.95] | 0.18 | |
Hodgkin’s lymphoma | |||||
HBV status | Positive | 4.15 [1.16, 14.90] | 0.03 | 3.32 [0.68, 16.21] | 0.14 |
Negative | Ref. | - | Ref. | - | |
CD4 count at diagnosis | /50 cells/mm3 higher | 0.86 [0.74, 1.01] | 0.06 | 0.80 [0.64, 0.99] | 0.04 |
Haemoglobin at diagnosis | /g/L higher | 0.72 [0.55, 0.94] | 0.02 | 0.82 [0.59, 1.14] | 0.24 |