Table 5 Baseline characteristic and therapy time of relapse and sustained response (SR) patients after discontinuation
Characteristic | SR (n=45) | Relapse (n=19) | P value |
|---|---|---|---|
HBV DNA - log10 IU/mL | 5.5±1.5 | 5.5±1.5 | 0.928 |
ALT – × ULN | 3.0 (1.5-6.3) | 1.5 (1.2-5.1) | 0.154 |
Age - years | 34±11 | 37±11 | 0.310 |
Man - no. (%) | 34 (75.6) | 14 (73.7) | 0.874 |
Time of achieving undetectable HBV DNA levels – weeks | 12 (12–24) | 16 (12–24) | 0.412 |
Consolidation therapy - weeks | 120 (96–156) | 144 (96–144) | 0.798 |
Genotype B - no. (%) | 19 (65.5) | 10 (34.5) | 0.445 |
Genotype C - no. (%) | 26 (74.3) | 9 (25.7) |