Table 4 Clinical characteristics, laboratory results, radiologic findings and disease extent among patients with tuberculosis (TB)
From: Apoptosis-associated biomarkers in tuberculosis: promising for diagnosis and prognosis prediction
| Â | Survivors n=79 | Non-survivors n=21 | p value |
|---|---|---|---|
Age (years) | 68.2 [16.9] | 78.3 [9.6] | 0.010 |
Male sex | 48 (61%) | 14 (67%) | 0.620 |
History of TB | 6 (8%) | 4 (19%) | 0.120 |
Co-morbidity | 27 (34%) | 12 (57%) | 0.055 |
Diabetes mellitus | 24 (30%) | 6 (29%) | 0.872 |
Malignancy | 6 (8%) | 9 (43%) | <0.001 |
Liver cirrhosis | 0 | 2 (10%) | 0.006 |
Diagnosis evidence | Â | Â | 0.051 |
Culture positive | 79 (100%) | 20 (95%) | Â |
Pathology positive | 0 | 1 (5%) | Â |
Mtb resistance | Â | Â | Â |
INH resistance | 8 (10%) | 0 | 0.128 |
RIF resistance | 0 | 1 (5%) | 0.051 |
Sputum AFS-positive | 52 (66%) | 11 (52%) | 0.257 |
Radiographic pattern | Â | Â | Â |
Upper lung lesion | 53 (67%) | 13 (62%) | 0.656 |
Cavitation | 11 (14%) | 1 (5%) | 0.251 |
Disease extent | Â | Â | 0.653 |
Pulmonary | 64 (81%) | 18 (86%) | Â |
Extra-pulmonary only | 3 (4%) | 0 | Â |
Mixed | 12 (15%) | 3 (14%) | Â |
Blood tests | Â | Â | Â |
Leukocyte, (/μL) | 9609 [4880] | 10297 [4207] | 0.542 |
Interleukin-6 | 54.9 [257.3] | 98.2 [196.6] | 0.408 |
Interleukin-10 | 5.6 [23.1] | 4.7 [12.2] | 0.814 |
Interferon-gamma | 66.3 [472.7] | 15.4 [38.9] | 0.347 |
TNF-alpha | 50.8 [375.5] | 32.7 [123.7] | 0.720 |
MCP-1 | 25.0 [50.1] | 68.2 [116.1] | 0.012 |
MIP-1alpha | 6.1 [29.8] | 1.8 [2.6] | 0.210 |
MIP-1beta | 245.4 [1274.7] | 193.3 [366.2] | 0.752 |
Decoy receptor 3 | 3.6 [3.8] | 5.3 [3.7] | 0.078 |
Lipoxin | 1.7 [1.5] | 1.7 [1.2] | 0.939 |
Prostaglandin E2 | 2.9 [8.1] | 3.4 [7.0] | 0.793 |