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Table 1 Peruvian syphilis treatment guidelines (non-pregnant)

From: Characterizing the syphilis epidemic among men who have sex with men in Lima, Peru to identify new treatment and control strategies

 

Treatment

Alternative

Primary

Penicillin G 2.4 million Units IM, single dose

Doxycyline 100 mg po bid × 2 weeks1

Secondary

Penicillin G 2.4 million Units IM, single dose

Doxycyline 100 mg po bid × 2 weeks1

Early latent

Penicillin G 2.4 million Units IM, single dose

Doxycyline 100 mg po bid × 2 weeks1

Late latent

Penicillin G 2.4 million Units IM, 3 weekly doses

Doxycyline 100 mg po bid × 4 weeks1

Tertiary

Penicillin G 2.4 million Units IM, 3 weekly doses

Doxycyline 100 mg po bid × 4 weeks1

Neurosyphilis

Penicillin G 4 million units IV q4h × 10–14 days

Penicillin Procaine 2.4 million units IM daily × 10–14 days with Probenecid 500 mg po four times daily × 10–14 days

  1. 1Tetracycline 500 mg po qid may be substituted for Doxycycline.