Table 1 Clinical and laboratory information of the patients in this study
Number | Percentage | |
|---|---|---|
Age, Median (IQR) | 57 (45-85)days | |
Male | 26 | 60.5% |
Female | 17 | 39.5% |
History | ||
Low birth weight (< 2,500 g) | 16 | 37.2% |
First-child | 26 | 60.5% |
Exclusive Breast fed | 23 | 53.5% |
Blood transfusion history | 5 | 11.6% |
Vaginal delivery | 36 | 83.7% |
Term infants (gestational age ≥38 weeks) | 25 | 58.1% |
Symptoms | ||
Weight (kg) | 3.83 ± 0.95 (1.9-6) | |
Malnourished | 5 | 11.6% |
Cough | 43 | 100% |
Diarrhea | 10 | 23.3% |
Wheeze | 43 | 100% |
Signs | ||
Body temperature ≥380C | 23 | 58.5% |
Sp02 <90% on room air | 32 | 74.4% |
Hepatomegaly | 26 | 60.5% |
Laboratory test | ||
CRP <0.6 mg/dl | 36 | 83.7% |
Hemoglobin <11 g/dl | 29 | 67.4% |
Leukocytosis >10,000 leukocyte /mm3 | 39 | 90.7% |
Aspartate aminotransferase (AST) > 40 IU/L | 32 | 74.4% |
Alanine aminotransferase (ALT) >37 IU/L | 19 | 41.2% |
Immunological data | ||
Positive for CMV-IgM | 29 | 67.4% |
Positive for CMV-IgG | 43 | 100% |
Low CD4 (<35% of T cell )* | 25/36 | 69.4% |
Low IgG level (<176 mg/dl)** | 9/35 | 25.7% |
CMV viral load | ||
CMV-DNA copies/mL in plasma, Median (IQR), 103 copies/mL | 59.5 (30-160) | |
CMV-DNA copies/mL in tracheal aspirates, Median (IQR), 103 copies/mL | 120 (7-4,000) | |
Chest X-ray | ||
Interstitial changes | 28 | 65.1% |
Interstitial and consolidation | 20 | 46.5% |
Consolidation | 5 | 11.6% |
Time interval between onset and visit ≥7 days, Median (IQR) | 15(10-21) | |
Outcome | ||
Discharged | 42 | 97.7% |
Died | 1 | 2.3% |