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Table 3 Average ratio of skewed TCRBV gene families in CD4 + and CD8 + T cell subsets of subjects with active TB or LTBI

From: Molecular characterization of T cell receptor beta variable in the peripheral blood T cell repertoire in subjects with active tuberculosis or latent tuberculosis infection

  Active TB LTBI
CD4+ T cells CD8+ T cells CD4+ T cells CD8+ T cells
Total no. of skewed TCRBV 143 117 123 76
Total no. of subjects detected 22 22 20 20
No. of subjects examined with normal pattern 1 1 1 2
Average ratio of skewed TCRBV (no. of subjects with skewed TCRBV) 6.81 (21)a 5.57 (21)b 6.47 (19)a 4.22 (18)b
  1. aThe rate of skewed TCRBV family was not significantly different between the two groups (P > 0.05 by χ2 test).
  2. bThe rate of skewed TCRBV family was higher in active TB group than that in LTBI group (P < 0.05 by χ2 test).