Skip to main content

Table 3 Average ratio of skewed TCRBV gene families in CD4 + and CD8 + T cell subsets of subjects with active TB or LTBI

From: Molecular characterization of T cell receptor beta variable in the peripheral blood T cell repertoire in subjects with active tuberculosis or latent tuberculosis infection

 

Active TB

LTBI

CD4+ T cells

CD8+ T cells

CD4+ T cells

CD8+ T cells

Total no. of skewed TCRBV

143

117

123

76

Total no. of subjects detected

22

22

20

20

No. of subjects examined with normal pattern

1

1

1

2

Average ratio of skewed TCRBV (no. of subjects with skewed TCRBV)

6.81 (21)a

5.57 (21)b

6.47 (19)a

4.22 (18)b

  1. aThe rate of skewed TCRBV family was not significantly different between the two groups (P > 0.05 by χ2 test).
  2. bThe rate of skewed TCRBV family was higher in active TB group than that in LTBI group (P < 0.05 by χ2 test).