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Table 2 The allele frequency of KIR3DS1 or KIR3DL1 between different groups

From: KIR3DS1/L1 and HLA-Bw4-80I are associated with HIV disease progression among HIV typical progressors and long-term nonprogressors

KIR alleles

1Low CD4

2High CD4

P

3High VL

4Low VL

P

5TP

6LTNP

P

 

n/166 (%)

n/98 (%)

 

n/168 (%)

n/96 (%)

 

n/166 (%)

n/80 (%)

 

KIR3DL1

142/166 (85.5)

73/98 (74.5)

0.02

141/168 (83.9)

74/96 (77.1)

0.11

142/166 (85.5)

59/80 (73.7)

0.03

KIR3DS1

24/166 (14.5)

25/98 (25.5)

0.02

27/168 (16.1)

22/96 (22.9)

0.11

24/166 (14.5)

21/80 (26.3)

0.03

  1. Data are the frequencies of KIR alleles (assuming the pairs 3DS1/3DL1 are alleles of respective loci).
  2. 1Low CD4, “low CD4+ T cell count” group (CD4+ T cell counts<500 cells/μl); 2High CD4, “High CD4+ T cell count” group (CD4+ T cell counts ≥ 500 cells/μl); 3High VL, “high viral load” group (HIV viral load ≥ 104 copies/ml); 4Low VL, “low viral load” group (HIV viral load<104 copies/ml); 5TP, HIV typical progressors; 6LTNP, HIV long-term nonprogressors (9 individuals were excluded for the analysis based on LTNPs or TPs, because of not meeting the criteria of LTNPs or TPs).
  3. Data was calculated by from Yates’s correction or Fisher’s exact test.
  4. Bold numbers indicate P value<0.05.