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Table 1 Distribution of KIR gene frequency 1 among individuals in different groups

From: KIR3DS1/L1 and HLA-Bw4-80I are associated with HIV disease progression among HIV typical progressors and long-term nonprogressors

KIRgene 2LowCD4 3High CD4 P 4High VL 5Low VL P 6TP 7LTNP P
(Total 83) (Total 49) (Total 84) (Total 48) (Total 83) (Total 40)
  n (%) n (%)   n (%) n (%)   n (%) n (%)  
KIR2DL1 80 (96.4) 47 (95.9) 0.615 81 (96.4) 46 (95.8) 0.601 80 (96.4) 40 (100.0) 0.304
KIR2DL2 43 (51.8) 32 (65.3) 0.091 46 (54.8) 29 (60.4) 0.328 43 (51.8) 26 (65.0) 0.117
KIR2DL3 81 (97.6) 46 (93.9) 0.266 82 (97.6) 45 (93.8) 0.253 81 (97.6) 40 (100.0) 0.454
KIR2DL4 82 (98.8) 49 (100.0) 0.629 83 (98.8) 47 (97.9) 0.597 82 (98.8) 40 (100.0) 0.675
KIR2DL5 35 (42.2) 22 (44.9) 0.450 36 (42.9) 21 (43.8) 0.532 35 (42.2) 18 (45.0) 0.458
KIR2DS1 34 (41.0) 26 (53.1) 0.122 36 (42.9) 24 (50.0) 0.270 34 (41.0) 21 (52.5) 0.156
KIR2DS2 23 (27.7) 12 (24.5) 0.424 19 (22.6) 16 (33.3) 0.128 23 (27.7) 9 (22.5) 0.350
KIR2DS3 13 (15.7) 11 (22.4) 0.227 15 (17.9) 9 (18.8) 0.537 13 (15.7) 11 (27.5) 0.097
KIR2DS4 81 (97.6) 46 (93.9) 0.266 82 (97.6) 45 (93.8) 0.253 81 (97.6) 37 (92.5) 0.194
KIR2DS5 26 (31.3) 18 (36.7) 0.326 27 (32.1) 17 (35.4) 0.422 26 (31.3) 14 (35.0) 0.417
KIR2DP1 80 (96.4) 47 (95.9) 0.615 81 (96.4) 46 (95.8) 0.601 80 (96.4) 40 (100.0) 0.304
KIR3DP1 83 (100.0) 48 (98.0) 0.371 84 (100.0) 47 (97.9) 0.364 83 (100.0) 39 (97.5) 0.325
KIR3DL1 81 (97.6) 46 (93.9) 0.266 82 (97.6) 45 (93.8) 0.253 81 (97.6) 37 (92.5) 0.194
KIR3DL2 83 (100.0) 49 (100.0)   84 (100.0) 48 (100.0)   83 (100.0) 40 (100.0)  
KIR3DL3 83 (100.0) 49 (100.0)   84 (100.0) 48 (100.0)   83 (100.0) 40 (100.0)  
KIR3DS1 22 (26.5) 22 (44.9) 0.025 25 (29.8) 19 (39.6) 0.169 22 (26.5) 18 (45.0) 0.033
  1. 1The frequency of individuals with at least one copy of the 16 KIR genes.
  2. 2Low CD4, “low CD4+ T cell count” group (CD4+ T cell counts ≥ 500 cells/μl); 3High CD4, “High CD4+ T cell count” group (CD4+ T cell counts<500 cells/μl); 4High VL, “high viral load” group (HIV viral load ≥ 104 copies/ml); 5Low VL, “low viral load” group (HIV viral load<104 copies/ml); 6TP, HIV typical progressors; 7LTNP, HIV long-term nonprogressors (9 individuals were excluded for the analysis based on LTNPs or TPs, because of not meeting the criteria of LTNPs or TPs).
  3. n, the number of individuals with each KIR gene in each group; %, the percentage of individuals with each KIR gene in each group.
  4. Data was calculated by from Yates’s correction or Fisher’s exact test.
  5. Bold numbers indicated P value<0.05.