Figure 4

Histopathological analysis in hind paw joints from C57L/6 mice infected with S. aureus strains . (a, a’) non-infected control. (b, b’) infected with ATCC 19095 SEC⁺. (c, c’) infected with N315 ST5 TSST-1⁺. (d, d’) infected with the S-70 TSST-1⁺. (a), (b), (c), (d) and (a’), (b’), (c ’), (d’) represent histopathological micrographics with 4x and 10x magnification, respectively. JC, joint cavity; C, cartilage; B, bone; BE, bone erosion; CE cartilage erosion; P, pannus formation and IC, inflammatory cells. Panel is representative of 5-9 animals/group.