Table 3 Association of HIV/HCV group with individually elevated (>75th percentile) biomarkers
Biomarker elevated | HIV/HCV group | Unadjusted OR (95% CI) | Adjusted ORa(95% CI) |
|---|---|---|---|
Model B (N = 218) | Undetectable | 1 | 1 |
Interleukin-10 | HIV mono-detectable | 4.74* (1.36, 16.48) | 2.95 (0.74, 11.85) |
HCV mono-detectable | 5.39* (1.39, 20.84) | 5.51* (1.17, 25.84) | |
HIV/HCV detectable | 9.22* (2.69, 31.55) | 7.79* (1.90, 31.97) | |
Model C (N = 218) | Undetectable | 1 | 1 |
Tumor necrosis factor-α | HIV mono-detectable | 4.50* (1.29, 15.70) | 4.44 (0.86, 22.82) |
HCV mono-detectable | 4.15* (1.04, 16.47) | 4.45 (0.68, 29.02) | |
HIV/HCV detectable | 8.50* (2.48, 29.16) | 7.70* (1.42, 41.83) | |
Model D (N = 196) | Undetectable | 1 | 1 |
Interleukin-6 | HIV mono-detectable | 1.33 (0.49, 3.66) | 0.57 (0.15, 2.16) |
HCV mono-detectable | 5.17* (1.79, 14.94) | 2.99 (0.75, 11.98) | |
HIV/HCV detectable | 3.33* (1.28, 8.70) | 1.47 (0.40, 5.35) | |
Model E (N = 218) | Undetectable | 1 | 1 |
Cystatin-C | HIV mono-detectable | 1.50 (0.56, 4.01) | 0.49 (0.12, 2.02) |
HCV mono-detectable | 2.22 (0.73, 6.73) | 0.40 (0.07, 2.34) | |
HIV/HCV detectable | 5.04* (1.98, 12.85) | 1.60 (0.39, 6.57) | |
Model F (N = 218) | Undetectable | 1 | 1 |
C-reactive protein | HIV mono-detectable | 1.16 (0.54, 2.51) | 0.99 (0.35, 2.84) |
HCV mono-detectable | 1.09 (0.42, 2.80) | 1.41 (0.41, 4.90) | |
HIV/HCV detectable | 0.86 (0.39, 1.90) | 0.69 (0.22, 2.14) | |
Model G (N = 210) | Undetectable | 1 | 1 |
Serum amyloid A | HIV mono-detectable | 0.81 (0.36, 1.80) | 0.58 (0.19, 1.79) |
HCV mono-detectable | 0.69 (0.25, 1.89) | 0.38 (0.09, 1.66) | |
HIV/HCV detectable | 1.01 (0.46, 2.22) | 0.72 (0.22, 2.31) | |
Model H (N = 218) | Undetectable | 1 | 1 |
Interferon-γ | HIV mono-detectable | 1.40 (0.52, 3.78) | 1.65 (0.46, 5.87) |
HCV mono-detectable | 1.68 (0.53, 5.28) | 2.63 (0.59, 11.76) | |
HIV/HCV detectable | 0.92 (0.32, 2.60) | 1.03 (0.25, 4.30) | |
Model I (N = 218) | Undetectable | 1 | 1 |
Monocyte chemoattractant protein-1 | HIV mono-detectable | 1.67 (0.72, 3.84) | 2.96 (0.80, 10.95) |
HCV mono-detectable | 1.38 (0.50, 3.79) | 3.71 (0.83, 16.53) | |
HIV/HCV detectable | 1.37 (0.59, 3.21) | 3.48 (0.88, 13.69) |