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Table 1 Characteristics of 361 HIV-LIVE participants with HIV infection and alcohol problems stratified by detectable HIV and HCV viremia

From: Human immunodeficiency virus, hepatitis C, and inflammatory biomarkers in individuals with alcohol problems: a cross-sectional study

Subject characteristics HIV/HCV RNA both undetectable (N = 59) HIV RNA only detectable (N = 122) HCV RNA only detectable (N = 53) HIV/HCV RNA both detectable (N = 127) p-value
Age in years, mean (SD) 43 (7) 40 (8) 46 (7) 43 (7) <0.01
Female 16 (27.1) 26 (21.3) 11 (20.8) 35 (27.6) 0.59
Race, Non-White 42 (71.2) 84 (68.9) 34 (64.2) 84 (66.1) 0.84
FIB-4 ≥ 1.45 7 (16.3) 28 (28.2) 22 (59.4) 52 (54.7) <0.01
FIB-4, Median (Min, Max) 0.9 (0.5, 3.1) 1.1 (0.2, 7.5) 1.6 (0.7, 14.9) 1.6 (0.4, 17.1) 0.30
FIB-4, Mean (Standard Deviation) 1.1 (0.5) 1.3 (1.0) 2.8 (2.9) 2.3 (2.2)  
Current at-risk alcohol consumption 15 (25.4) 46 (38.0) 9 (17.0) 43 (33.9) 0.03
Current CD4+ T-lymphocyte count <200 cells/mm 3 4 (6.8) 27 (22.9) 6 (11.8) 34 (26.8) <0.01
Current antiretroviral medication 52 (88.1) 56 (45.9) 50 (94.3) 65 (51.2) <0.01
BMI ≥30 kg/m 2 13 (22.8) 23 (19.8) 8 (15.1) 25 (21.2) 0.76
Prevalent cardiovascular disease 3 (5.1) 2 (1.6) 6 (11.3) 15 (11.9) <0.01
Ever had diabetes 2 (3.4) 6 (4.9) 9 (17.0) 9 (7.1) 0.02
Ever had hypertension 16 (27.1) 28 (23.0) 14 (26.4) 33 (26.0) 0.91
Ever had high cholesterol 29 (49.2) 32 (26.2) 11 (20.8) 25 (19.7) <0.01
Ever had kidney disease 2 (3.4) 5 (4.1) 5 (9.4) 9 (7.1) 0.40
Ever anemic 17 (28.8) 28 (23.0) 12 (22.6) 31 (24.4) 0.84
Current smoker 39 (66.1) 93 (76.2) 40 (75.5) 102 (80.3) 0.22
Ever cocaine use 23 (39.0) 53 (43.4) 18 (34.0) 65 (51.2) 0.14
Ever injection drug use 10 (17.0) 26 (21.5) 46 (86.8) 115 (90.6) <0.01
Ever treated hepatitis C 0 (0) 3 (2.5) 8 (15.1) 6 (4.7) <0.01
  1. All values are n (% of HIV/HCV group) unless otherwise specified.
  2. HIV human immunodeficiency virus, HCV hepatitis C virus, FIB 4-liver fibrosis index-4, BMI body mass index.
  3. The number of people with available FIB-4 measurements was 43 (HIV/HCV both undetectable), 99 (HIV only detectable), 37 (HCV only detectable), 95 (HIV/HCV both detectable).
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