TY - JOUR AU - Armah, Kaku A. AU - Quinn, Emily K. AU - Cheng, Debbie M. AU - Tracy, Russell P. AU - Baker, Jason V. AU - Samet, Jeffrey H. AU - Freiberg, Matthew S. PY - 2013 DA - 2013/08/29 TI - Human immunodeficiency virus, hepatitis C, and inflammatory biomarkers in individuals with alcohol problems: a cross-sectional study JO - BMC Infectious Diseases SP - 399 VL - 13 IS - 1 AB - Assessing whether hepatitis C (HCV) co-infection with human immunodeficiency virus (HIV) is associated with increased inflammation is complex. The liver, integral to inflammatory biomarker synthesis, is compromised by HCV and alcohol abuse. Using single liver-synthesized biomarkers (e.g. C-reactive protein) to represent inflammation may not be appropriate in HIV/HCV co-infection. We hypothesized that 1) detectable HIV/HCV RNA was independently associated with increased inflammation; 2) a composite inflammation measure describes inflammation differently from single inflammatory biomarkers. SN - 1471-2334 UR - https://doi.org/10.1186/1471-2334-13-399 DO - 10.1186/1471-2334-13-399 ID - Armah2013 ER -