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Figure 1 | BMC Infectious Diseases

Figure 1

From: Vitamin B6 reduces hippocampal apoptosis in experimental pneumococcal meningitis

Figure 1

Schematic of the kynurenine pathway in the rat brain. Tryptophan is metabolized over multiple steps into quinolinic acid, finally resulting in de novo synthesis of NAD+. Several neuroactive intermediates are included in this pathway: neuroprotective kynurenic acid, neurotoxic 3-hydroxykynurenine and neurotoxic 3-hydroxyanthranilic acid. Neurotoxic intermediates are written in red, neuroprotective ones in green [6, 7].

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