Figure 1

Mononucleotide BLSOM for influenza A and B genome sequences. (A) Mono. Mono-BLSOM was constructed for 12,067 influenza A and 328 B strains. Lattice points containing sequences from strains isolated from more than one host were indicated in black, and those containing sequences from one host were indicated in a color representing the host: avian (3,752 strains) colored in red, human (7,434 strains) in green, swine (783 strains) in blue, equine (95 strains), bat (3 strains) in grey, and influenza B virus (328 strains) in light blue. (B) Hum Sub. On the Mono-BLSOM, strains of each human subtype were specified in a color representing the subtype (H1N1 colored in light blue, H1N1/09 in dark green, H2N2 in geen, H3N2 in blue, H5N1 in brown, H7 in pink, H9 in pink, and others in green), and strains isolated from other animal hosts were achromatic. (Ci-iv) Occurrences of each mononucleotide at individual lattice points were sorted and classified into 21 groups and differing levels were indicated with different colors presented below the figure: wine red (high), dark green (low) and achromatic (intermediate).