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Table 1 Definition of the RIFLE criteria to assess AKI

From: Trough colistin plasma level is an independent risk factor for nephrotoxicity: a prospective observational cohort study

Category criteria Definition
Risk (R) Increased creatinine level × 1.5 or GFR decrease > 25%
Injury (I) Increased creatinine level × 2 or GFR decrease > 50%
Failure (F) Increased creatinine level × 3, GFR decrease > 75%, or creatinine level > 4 mg/dL
Loss (L) Persistent acute renal failure or loss of function for > 4 weeks
End-Stage Kidney Disease (ESKD) (E) ESKD for > 3 months
  1. *GFR, glomerular filtration rate.