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Table 2 Human papillomavirus genotype-specific prevalences among invasive cervical cancer cases, meta-analytical estimates of relative oncogenic potentials

From: Comparing human papillomavirus prevalences in women with normal cytology or invasive cervical cancer to rank genotypes according to their oncogenic potential: a meta-analysis of observational studies

HPV- Prevalence*   Cases†, n Pooled OR 95% CI Studies‡, n Cochran’s Q -test P I2statistic, % Between-study variance
  n (%)
6 17 (0.8) 2,208 0.08 0.04, 0.16 18 0.162 24.8 0.438
11 17 (1.1) 1,554 0.11 0.06, 0.19 15 0.407 4.1 0.049
16 1,680 (57.9) 2,902   Reference 27    
18 372 (12.8) 2,902 0.63 0.51, 0.78 27 0.425 2.6 0.009
30 2 (0.5) 430 0.13 0.03, 0.60 3 0.881 0.0 0.000
31 122 (4.4) 2,745 0.22 0.14, 0.35 24 <0.001 55.9 0.696
33 128 (4.7) 2,728 0.22 0.12, 0.38 24 <0.001 65.1 1.152
34 1 (0.2) 666 0.21 0.06, 0.80 5 0.791 0.0 0.000
35 67 (2.7) 2,450 0.12 0.08, 0.17 21 0.408 4.0 0.032
39 24 (1.2) 2,017 0.17 0.09, 0.30 19 0.169 23.7 0.372
40 2 (0.2) 991 0.13 0.04, 0.45 8 0.197 28.9 0.889
42 3 (0.2) 1,573 0.05 0.02, 0.15 11 0.102 37.2 1.345
44 3 (0.4) 729 0.14 0.03, 0.66 5 0.147 41.1 1.324
45 119 (4.8) 2,464 0.35 0.22, 0.55 23 0.054 34.4 0.358
51 54 (2.7) 1,971 0.10 0.05, 0.20 19 0.014 46.3 0.901
52 96 (4.0) 2,394 0.16 0.11, 0.23 21 0.293 12.7 0.091
53 22 (1.1) 1,981 0.07 0.04, 0.12 16 0.380 6.4 0.075
54 1 (0.1) 1,263 0.06 0.02, 0.16 9 0.580 0.0 0.000
56 22 (1.0) 2,303 0.09 0.05, 0.16 20 0.278 14.2 0.230
58 127 (4.7) 2,685 0.24 0.15, 0.38 22 <0.001 56.8 0.583
59 24 (1.1) 2,218 0.17 0.09, 0.31 16 0.537 0.0 0.000
61 2 (0.2) 1,130 0.05 0.02, 0.14 8 0.739 0.0 0.000
62 1 (0.2) 558 0.07 0.02, 0.23 6 0.420 0.0 0.000
66 16 (0.7) 2,181 0.08 0.05, 0.14 18 0.799 0.0 0.000
67 4 (0.3) 1,342 0.21 0.06, 0.67 10 0.181 28.6 1.020
68 8 (0.5) 1,661 0.07 0.04, 0.14 14 0.439 0.8 0.013
69 9 (1.3) 672 0.28 0.09, 0.92 5 0.249 25.8 0.473
70 6 (0.4) 1,496 0.07 0.03, 0.14 11 0.565 0.0 0.000
71 1 (0.1) 672 0.03 0.01, 0.13 4 0.527 0.0 0.000
73 8 (0.7) 1,151 0.16 0.06, 0.41 10 0.617 0.0 0.000
74 1 (0.4) 264 0.10 0.00, 3.41 2 0.051 73.8 4.874
81 1 (0.1) 1,257 0.04 0.02, 0.10 11 0.966 0.0 0.000
82 4 (0.4) 892 0.13 0.04, 0.36 7 0.939 0.0 0.000
  1. *HPV prevalence among cases, with no distinction between simple and multiple infections, across the studies that reported counts of the HPV genotypes under consideration. †Number of cases tested for the given HPV genotype. ‡Number of studies included in each meta-analysis. Abbreviations: HPV human papilloma virus, OR odds ratio, CI confidence interval.
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BMC Infectious Diseases

ISSN: 1471-2334

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