TY - JOUR AU - Berrington, William R. AU - Smith, Kelly D. AU - Skerrett, Shawn J. AU - Hawn, Thomas R. PY - 2013 DA - 2013/08/10 TI - Nucleotide-binding oligomerization domain containing-like receptor family, caspase recruitment domain (CARD) containing 4 (NLRC4) regulates intrapulmonary replication of aerosolized Legionella pneumophila JO - BMC Infectious Diseases SP - 371 VL - 13 IS - 1 AB - Legionella pneumophila (Lp) flagellin activates signaling pathways in murine macrophages that control Lp replication. Nucleotide-binding oligomerization domain (NOD) containing-like receptor (NLR) family, caspase recruitment domain (CARD) containing 4 (NLRC4) and Toll-like Receptor (TLR5) both recognize Lp flagellin in vitro, but whether these two receptors play redundant or separate functional roles in vivo is unknown. SN - 1471-2334 UR - https://doi.org/10.1186/1471-2334-13-371 DO - 10.1186/1471-2334-13-371 ID - Berrington2013 ER -