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Table 1 Characteristics of patients with MRSA and non-MRSA pneumonia a

From: Prediction of methicillin-resistant Staphylococcus aureusin patients with non-nosocomial pneumonia

Characteristics MRSA Non-MRSA P-value
(n=78) (n=865)
Age 71.4 ± 9.3 66.0 ± 14.8 < 0.001
Male 58 (74.4) 565 (65.3) 0.106
Female 20 (25.6) 300 (34.7)
Type of pneumonia    
   Community acquired 21 (26.9) 475 (54.9) < 0.001
   Health care associated 57 (73.1) 390 (45.1)
Underlying diseases    
   Diabetes mellitus 30 (38.5) 237 (27.4) 0.038
   Chronic lung diseaseb 20 (25.6) 239 (27.6) 0.706
   Cerebral vascular accident 22 (28.2) 162 (18.7) 0.043
   Renal disease 14 (17.9) 104 (12.0) 0.13
   Hypertension 44 (9.7) 408 (47.2) 0.118
   Cardiovascular disease 21 (26.9) 148 (17.1) 0.03
   Liver disease 6 (7.7) 50 (5.8) 0.454
   Rheumatologic disease 3 (3.8) 31 (3.6) 0.756
   Malignancy 36 (46.2) 303 (35.0) 0.05
Clinical manifestation and parameters    
   Bloody sputum 1 (1.3) 42 (4.9) 0.147
   Confusion (decreased consciousness) 17 (21.8) 134 (15.5) 0.146
   Shock at onset 20 (25.6) 267 (30.9) 0.337
   Hypoxemiac 49 (62.8) 437 (50.5) 0.037
   Acute renal failure at onset 13 (16.7) 162 (18.7) 0.654
   Leukocytes /uL 12700 ± 7700 11800 ± 7300 0.341
   Blood urea nitrogen > 30 mg/dL 25 (32.1) 255 (29.5) 0.634
   Sodium < 130 mmol/L 15 (19.2) 132 (15.3) 0.355
   pH < 7.35 7 (9) 72 (8.3) 0.843
Immunosuppressedd 24 (30.8) 215 (24.9) 0.25
MRSA history in previous 1 year 20 (25.6) 33 (3.8) < 0.001
Tube feeding 12 (15.4) 64 (7.4) 0.013
CURB65 1.94 ± 1.07 1.6 ± 1.15 0.015
Pneumonia Severity Index 144.7 ± 26.1 127.6 ± 38.4 < 0.001
Admission via ER 64 (82.1) 700 (80.9) 0.808
  1. aData are presented as numbers (percentages) and plus-minus values are means ± standard deviation unless otherwise indicated.
  2. bChronic lung disease includes asthma, COPD, and structural lung diseases, such as bronchiectasis and interstitial lung disease.
  3. cPaO2 < 60 mmHg, SpO2 < 90% or need for oxygen therapy.
  4. dImmunosuppression includes the following: (1) daily administration of systemic corticosteroids (at least 15 mg of prednisone per day for more than one month or combination therapy with low dose corticosteroids and other immunosuppressants including azathioprine, mycophenolate, methotrexate, cyclosporine, or cyclophosphamide); (2) seropositivity for human immunodeficiency virus; (3) received either a solid organ transplant or bone marrow transplant; (4) treated with radiation therapy or chemotherapy for an underlying malignancy during the 6 months prior to hospital admission; (5) an underlying acquired immune deficiency disorder.
  5. Abbreviations: MRSA methicillin-resistant Staphylococcus aureus, ER emergency room.