Variables | Cases (n = 62) | Controls (n = 186) | OR (95% CI) | P |
---|---|---|---|---|
Age (± SD) | 63.77 (± 14.58) | 63.58 (± 14.34) | ||
Male sex | 45 (72.6) | 135 (72.6) | ||
Urinary tract infection | 7 (11.3) | 20 (10.8) | 1.05 (0.43-2.58) | 0.908 |
Intra-abdominal infection | 12 (19.4) | 22 (11.8) | 1.82 (0.83-4.00) | 0.136 |
Biliary tract infection | 13 (21.0) | 53 (28.5) | 0.65 (.032-1.32) | 0.236 |
Liver abscess | 8 (12.9) | 31 (16.7) | 0.73 (0.31-1.72) | 0.469 |
Pneumonia | 8 (12.9) | 18 (9.7) | 1.36 (0.57-3.20) | 0.487 |
Primary bacteremia | 9 (14.5) | 34 (18.3) | 0.73 (0.31-1.72) | 0.474 |
Central venous catheter related infection | 2 (3.2) | 4 (2.2) | 1.50 (0.28-8.19) | 0.640 |
Charlson’s CWI score (± SD) | 6.29 (± 3.05) | 5.52 (± 2.94) | 1.14 (1.01-1.28) | 0.037 |
ICU admission | 18 (29.0) | 30 (16.1) | 2.12 (1.08-4.16) | 0.029 |
Presentation with septic shock | 22 (35.5) | 53 (28.5) | 1.35 (0.75-2.44) | 0.316 |
APACHE-II score (± SD) | 18.97 (± 9.28) | 17.09 (± 8.16) | 1.03 (0.99-1.06) | 0.140 |
Pitt bacteremia score (± SD) | 2.45 (± 2.67) | 2.17 (± 2.45) | 1.04 (0.94-1.16) | 0.452 |
Nosocomial infection | 34 (54.8) | 55 (29.6) | 2.96 (1.61-5.43) | <0.001 |
Previous antibiotic use ≤ 1 year | 37 (59.7) | 95 (51.1) | 1.42 (0.79-2.54) | 0.240 |
Immunosuppressive therapy ≤ 1 year | 5 (8.1) | 4 (2.2) | 4.46 (1.05-18.95) | 0.043 |
History of solid organ transplantation | 4 (6.5) | 2 (1.1) | 10.18 (1.11-93.02) | 0.040 |
Invasive procedure ≤ 72 hours before initial BC | 20 (32.3) | 30 (16.1) | 2.56 (1.29-5.07) | 0.007 |
Neutropenia ≤ 72 hours before initial BC | 11 (17.7) | 31 (16.7) | 1.08 (0.50-2.33) | 0.843 |
Presence of metastatic infection | 5 (8.1) | 9 (4.8) | 1.67 (0.56-4.97) | 0.360 |
Inappropriate drainage | 11 (17.7) | 20 (10.8) | 1.81 (0.80-4.07) | 0.154 |
Fever on the 2 nd day after initial BC | 38 (61.3) | 46 (24.7) | 5.18 (2.64-10.16) | <0.001 |
Leukocytosis on the 2nd day after initial BC | 23 (37.1) | 60 (32.3) | 1.22 (0.68-2.19) | 0.499 |
Lack of CRP decrease on the 2 nd day after initial BC | 26 (41.9) | 43 (23.1) | 2.38 (1.29-4.39) | 0.010 |
Unfavorable treatment response on the 2 nd day after initial BC | 27 (43.5) | 30 (16.1) | 4.69 (2.27-9.69) | <0.001 |
ESBL-producing Klebsiella pneumoniae bacteremia | 28 (45.2) | 31 (16.7) | 3.99 (2.09-7.63) | <0.001 |
Inappropriate empirical antibiotic use | 22 (35.5) | 24 (12.9) | 4.02 (1.95-8.31) | <0.001 |
Length of time to empirical antibiotic administration from initial BC (minute, ± SD) | 182.8 (± 221.3) | 228.4 (± 434.8) | 1.00 (0.99-1.00) | 0.430 |
In-hospital mortality | 19 (30.6) | 34 (18.3) | 1.96 (1.02-3.78) | 0.044 |
Length of hospital stay (day, ± SD) | 45.1 (± 43.0) | 38.6 (± 74.9) | 1.00 (0.99-1.01) | 0.524 |