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Table 1 Antimicrobial susceptibility of 65 Neisseria gonorrhoeae isolates from India (n=40), Pakistan (n=18), and Bhutan (n=7) in 2007–2011

From: Antimicrobial susceptibility and genetic characteristics of Neisseria gonorrhoeae isolates from India, Pakistan and Bhutan in 2007–2011

Antimicrobial Breakpoints (susceptible/resistant, mg/L) MIC range (mg/L) Resistant, number (%) Intermediate susceptible, number (%) Susceptible, number (%)
Ciprofloxacin S≤0.03/R>0.06a 0.064->32 61 (93.8) 4 (6.2) 0 (0)
Penicillin Gb S≤0.06/R>1a 0.016->32 44 (67.7) 20 (30.8) 1 (1.5)
Erythromycinc S≤0.25/R>0.5c 0.032-128 40 (61.5) 8 (12.3) 17 (26.2)
Tetracycline S≤0.5/R>1a 0.125-64 36 (55.4) 22 (33.8) 7 (10.8)
Azithromycin S≤0.25/R>0.5a 0.016-4 5 (7.7) 10 (15.4) 50 (76.9)
Spectinomycin S≤64/R>64a 4-16 0 (0) 0 (0) 65 (100)
Ceftriaxone S≤0.12/R>0.12a <0.002-0.064 0 (0) 0 (0) 65 (100)
Cefixime S≤0.12/R>0.12a <0.016-0.064 0 (0) 0 (0) 65 (100)
  1. aBreakpoints according to The European Committee on Antimicrobial Susceptibility Testing. (EUCAST (http://www.eucast.org; Clinical breakpoints v2.0)).
  2. bβ-lactamase was produced by 34 (52%) of the examined isolates, and all these isolates were considered as resistant to penicillin G independent on their MIC values.
  3. cBecause of the lack of EUCAST breakpoints, the EUCAST breakpoints for azithromycin were used also for erythromycin.
  4. MIC, minimum inhibitory concentration.