Table 3 Information available at admission predictivefor ≥ 1 organ failure within one day
From: Age-related differences in symptoms, diagnosis and prognosis of bacteremia
Patients without organ failure(342 patients;%within this group) | Patients with organ failure(290 patients;%within this group) | Bivariate analyses OR(95% CI) | Multivariate analysis; full maineffects’model*OR(95%CI) | |
|---|---|---|---|---|
Age ≥ 65 years | 204 (59.6) | 215 (74.1) | 1.94 (1.38-2.73) | 1.65 (1.09 - 2.49) |
Male gender | 137 (40.1) | 135 (46.6) | 1.30 (0.95 – 1.79) | |
No. of comorbid illnesses | - | - | 1.41 (1.23-1.61) | 1.19 (1.02 - 1.40) |
Corticosteroid on a daily basis1 | 8 (2.4) | 23 (8.0) | 3.55 (1.56 – 8.05) | 2.75 (1.10 - 6.89) |
Cytostatic treatment within last 14 days | 1 (0.3) | 6 (2.1) | 7.10 (0.85 - 59.34) | |
Immunosuppressive treatment | 1 (0.3) | 5 (1.7) | 5.90 (0.69 - 50.77) | |
Number of symptoms ≥ 5 | 35 (10.2) | 41 (14.2) | 1.45 (0.90 – 2.35) | |
“Classical symptoms”2 ≥ 3 | 141 (41.3) | 97 (33.7) | 0.72 (0.52 - 0.99) | 0.67 (0.45 - 0.99) |
“Atypical symptoms”3 ≥ 1 | 151 (44.2) | 169 (58.3) | 1.77 (1.29 - 2.42) | |
Decline in general health (as described in the emergencydepartment) | 112 (32.8) | 166 (57.2) | 2.74 (1.98 - 3.79) | 2.28 (1.58 - 3.27) |
Heart rate > 90 beats per minute | 197 (58.5) | 203 (70.7) | 1.72 (1.23 - 2.40) | 1.50 (1.02 - 2.20) |
Fever (≥ 38.5°C) | 229 (68.4) | 178 (62.2) | 0.76 (0.55 - 1.06) | |
Hypothermia (< 36°C) | 4 (1.2) | 6 (2.1) | 1.77 (0.50 - 6.35) | |
Tachypnoe and/or hyperventilation | 78 (22.8) | 167 (57.6) | 4.60 (3.26 - 6.48) | 3.86 (2.64 - 5.66) |
Leukocytosis (≥ 15000/μl) | 145 (42.4) | 118 (40.7) | 0.93 (0.68 - 1.28) | |
Leukopenia (< 3000/μl) | 6 (1.8) | 31 (10.7) | 6.70 (2.76 - 16.31) | 4.16 (1.59 - 10.91) |
CRP ≥ 80 mg/L | 253 (74.0) | 233 (80.3) | 1.44 (0.99 - 2.10) | |
CRP ≥ 200 mg/L | 157 (45.9) | 153 (52.8) | 1.32 (0.96 -1.80) | |
New-onset atrial fibrillation | 35 (10.4) | 64 (22.1) | 2.45 (1.57 - 3.82) |