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Table 2 Site and severity of infection by 3 age groups

From: Age-related differences in symptoms, diagnosis and prognosis of bacteremia

  

Age groups (% within age group)

 
 

Total material (680 patients)

< 65 years

(228 patients)

65-84 years

(334 patients)

≥ 85 years

(118 patients)

Overall p-value

Acute organ failure within 1 day after admission

     

  No. of acute organ failures; mean (95% CI))

0.69 (0.62 – 0.76)

0.53 (0.41 – 0.64)

0.80 (0.70 – 0.90)*

0.70 (0.53-0.88)

0.003

  Presence of ≥ 1 organ failure

290 (45.9%)

75 (35.2%)

165 (53.1%)*

50 (46.4%)

< 0.001

  Type of acute organ failure

     

      Cardiovascularfailure

80 (11.8%)

21 (9.3%)

50 (15.0%)*

9 (7.6%)

0.035

      Respiratory failure

192 (28.2%)

54 (23.7%)

102 (30.5%)

36 (30.5%)

0.173

      Acute renal failure

30 (4.5%)

6 (2.7%)

20 (6.1%)

4 (3.4%)

0.144

      Coagulation failure

54 (8.4%)

14 (6.5%)

32 (10.1%)

8 (7.3%)

0.299

      (platelets <100x103/mm3)

     

      Reducedconsciousness

99 (14.6%)

19 (8.3%)

55 (16.5%)*

25 (21.4%)*

0.002

Sepsis-diagnosis at discharge

     

  Sepsis as main or side diagnosis (ICD-9 orICD-10)

313 (46.0%)

86 (37.7%)

171 (51.2%)*

56 (47.5%)

0.007

Site of infection

     

  Urinary tract

255 (37.5%)

84 (36.8%)

132 (39.5%)

39 (33.1%)

0.445

  Respiratory system

228 (33.5%)

94 (41.2%)

95 (28.4%)*

39 (33.1%)

0.007

  Other sites1

107 (15.7%)

32 (14.0%)

61 (18.3%)

14 (11.9%)

0.179

  Inconclusive

90 (13.2)

18 (7.9%)

46 (13.8%)*

26 (22.0%)*

0.001

Hospital stay

     

  Department responsible at admission:

     

      Surgical department(urology included)

138 (20.3%)

60 (26.3%)

61 (18.3%)

17 (14.4%)

0.006

      Medical department

525 (77.2%)

161 (70.6%)

268 (80.2%)

96 (81.4%)

 

      Other departments; andmissing

17 (2.5%)

7 (3.1%)

5 (1.5%)

5 (4.2%)

 

  Transferred to an ICU within 1 day afteradmission

153 (22.5%)

55 (24.1%)

82 (24.6%)

16 (13.6%)*

0.038

  Length of stay in days; median (IQR)

8 (5–14)

7 (5–11)

9 (6–16)*

9 (5–15)

0.008

In-hospital mortality

     

  Total in-hospital mortality

92 (13.5%)

12 (5.3%)

62 (18.6%)*

18 (15.3%)*

<0.001

  Day of in-hospital death; median (IQR)

5 (1–12)

16.5 (2.25 - 22.75)

6 (1–11.25)

2 (0.75 - 7)

0.065

  Early in-hospital mortality (within 3 days afteradmission)

39 (5.7%)

4 (1.8%)

23 (6.9%)*

12 (10.2%)*

0.003

  In-hospital mortality within 14 days afteradmission

72 (10.6%)

6 (2.6%)

51 (15.3%)*

15 (12.7%)*

<0.001

One-year mortality

168 (24.7%)

30 (13.2%)

101 (30.3%)*

37 (31.4%)*

<0.001

  1. 1 Gastrointestinal tract, liver, pancreas and biliary tract.* Significantly different from the age group < 65, which was treatedas reference group.