From: Age-related differences in symptoms, diagnosis and prognosis of bacteremia
 |  | Age groups (% within age group) |  | ||
---|---|---|---|---|---|
 | Total material (680 patients) | < 65 years (228 patients) | 65-84 years (334 patients) | ≥ 85 years (118 patients) | Overall p-value |
Acute organ failure within 1 day after admission | Â | Â | Â | Â | Â |
  No. of acute organ failures; mean (95% CI)) | 0.69 (0.62 – 0.76) | 0.53 (0.41 – 0.64) | 0.80 (0.70 – 0.90)* | 0.70 (0.53-0.88) | 0.003 |
  Presence of ≥ 1 organ failure | 290 (45.9%) | 75 (35.2%) | 165 (53.1%)* | 50 (46.4%) | < 0.001 |
  Type of acute organ failure |  |  |  |  |  |
      Cardiovascularfailure | 80 (11.8%) | 21 (9.3%) | 50 (15.0%)* | 9 (7.6%) | 0.035 |
      Respiratory failure | 192 (28.2%) | 54 (23.7%) | 102 (30.5%) | 36 (30.5%) | 0.173 |
      Acute renal failure | 30 (4.5%) | 6 (2.7%) | 20 (6.1%) | 4 (3.4%) | 0.144 |
      Coagulation failure | 54 (8.4%) | 14 (6.5%) | 32 (10.1%) | 8 (7.3%) | 0.299 |
      (platelets <100x103/mm3) |  |  |  |  |  |
      Reducedconsciousness | 99 (14.6%) | 19 (8.3%) | 55 (16.5%)* | 25 (21.4%)* | 0.002 |
Sepsis-diagnosis at discharge | Â | Â | Â | Â | Â |
  Sepsis as main or side diagnosis (ICD-9 orICD-10) | 313 (46.0%) | 86 (37.7%) | 171 (51.2%)* | 56 (47.5%) | 0.007 |
Site of infection | Â | Â | Â | Â | Â |
  Urinary tract | 255 (37.5%) | 84 (36.8%) | 132 (39.5%) | 39 (33.1%) | 0.445 |
  Respiratory system | 228 (33.5%) | 94 (41.2%) | 95 (28.4%)* | 39 (33.1%) | 0.007 |
  Other sites1 | 107 (15.7%) | 32 (14.0%) | 61 (18.3%) | 14 (11.9%) | 0.179 |
  Inconclusive | 90 (13.2) | 18 (7.9%) | 46 (13.8%)* | 26 (22.0%)* | 0.001 |
Hospital stay | Â | Â | Â | Â | Â |
  Department responsible at admission: |  |  |  |  |  |
      Surgical department(urology included) | 138 (20.3%) | 60 (26.3%) | 61 (18.3%) | 17 (14.4%) | 0.006 |
      Medical department | 525 (77.2%) | 161 (70.6%) | 268 (80.2%) | 96 (81.4%) |  |
      Other departments; andmissing | 17 (2.5%) | 7 (3.1%) | 5 (1.5%) | 5 (4.2%) |  |
  Transferred to an ICU within 1 day afteradmission | 153 (22.5%) | 55 (24.1%) | 82 (24.6%) | 16 (13.6%)* | 0.038 |
  Length of stay in days; median (IQR) | 8 (5–14) | 7 (5–11) | 9 (6–16)* | 9 (5–15) | 0.008 |
In-hospital mortality | Â | Â | Â | Â | Â |
  Total in-hospital mortality | 92 (13.5%) | 12 (5.3%) | 62 (18.6%)* | 18 (15.3%)* | <0.001 |
  Day of in-hospital death; median (IQR) | 5 (1–12) | 16.5 (2.25 - 22.75) | 6 (1–11.25) | 2 (0.75 - 7) | 0.065 |
  Early in-hospital mortality (within 3 days afteradmission) | 39 (5.7%) | 4 (1.8%) | 23 (6.9%)* | 12 (10.2%)* | 0.003 |
  In-hospital mortality within 14 days afteradmission | 72 (10.6%) | 6 (2.6%) | 51 (15.3%)* | 15 (12.7%)* | <0.001 |
One-year mortality | 168 (24.7%) | 30 (13.2%) | 101 (30.3%)* | 37 (31.4%)* | <0.001 |