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Table 2 Site and severity of infection by 3 age groups

From: Age-related differences in symptoms, diagnosis and prognosis of bacteremia

   Age groups (% within age group)  
  Total material (680 patients) < 65 years
(228 patients)
65-84 years
(334 patients)
≥ 85 years
(118 patients)
Overall p-value
Acute organ failure within 1 day after admission      
  No. of acute organ failures; mean (95% CI)) 0.69 (0.62 – 0.76) 0.53 (0.41 – 0.64) 0.80 (0.70 – 0.90)* 0.70 (0.53-0.88) 0.003
  Presence of ≥ 1 organ failure 290 (45.9%) 75 (35.2%) 165 (53.1%)* 50 (46.4%) < 0.001
  Type of acute organ failure      
      Cardiovascularfailure 80 (11.8%) 21 (9.3%) 50 (15.0%)* 9 (7.6%) 0.035
      Respiratory failure 192 (28.2%) 54 (23.7%) 102 (30.5%) 36 (30.5%) 0.173
      Acute renal failure 30 (4.5%) 6 (2.7%) 20 (6.1%) 4 (3.4%) 0.144
      Coagulation failure 54 (8.4%) 14 (6.5%) 32 (10.1%) 8 (7.3%) 0.299
      (platelets <100x103/mm3)      
      Reducedconsciousness 99 (14.6%) 19 (8.3%) 55 (16.5%)* 25 (21.4%)* 0.002
Sepsis-diagnosis at discharge      
  Sepsis as main or side diagnosis (ICD-9 orICD-10) 313 (46.0%) 86 (37.7%) 171 (51.2%)* 56 (47.5%) 0.007
Site of infection      
  Urinary tract 255 (37.5%) 84 (36.8%) 132 (39.5%) 39 (33.1%) 0.445
  Respiratory system 228 (33.5%) 94 (41.2%) 95 (28.4%)* 39 (33.1%) 0.007
  Other sites1 107 (15.7%) 32 (14.0%) 61 (18.3%) 14 (11.9%) 0.179
  Inconclusive 90 (13.2) 18 (7.9%) 46 (13.8%)* 26 (22.0%)* 0.001
Hospital stay      
  Department responsible at admission:      
      Surgical department(urology included) 138 (20.3%) 60 (26.3%) 61 (18.3%) 17 (14.4%) 0.006
      Medical department 525 (77.2%) 161 (70.6%) 268 (80.2%) 96 (81.4%)  
      Other departments; andmissing 17 (2.5%) 7 (3.1%) 5 (1.5%) 5 (4.2%)  
  Transferred to an ICU within 1 day afteradmission 153 (22.5%) 55 (24.1%) 82 (24.6%) 16 (13.6%)* 0.038
  Length of stay in days; median (IQR) 8 (5–14) 7 (5–11) 9 (6–16)* 9 (5–15) 0.008
In-hospital mortality      
  Total in-hospital mortality 92 (13.5%) 12 (5.3%) 62 (18.6%)* 18 (15.3%)* <0.001
  Day of in-hospital death; median (IQR) 5 (1–12) 16.5 (2.25 - 22.75) 6 (1–11.25) 2 (0.75 - 7) 0.065
  Early in-hospital mortality (within 3 days afteradmission) 39 (5.7%) 4 (1.8%) 23 (6.9%)* 12 (10.2%)* 0.003
  In-hospital mortality within 14 days afteradmission 72 (10.6%) 6 (2.6%) 51 (15.3%)* 15 (12.7%)* <0.001
One-year mortality 168 (24.7%) 30 (13.2%) 101 (30.3%)* 37 (31.4%)* <0.001
  1. 1 Gastrointestinal tract, liver, pancreas and biliary tract.* Significantly different from the age group < 65, which was treatedas reference group.