Variable | No. dead at day 14 (%) | RR(95% CI) | P value | No. dead at day 30 (%) | RR (95% CI) | P value | |
---|---|---|---|---|---|---|---|
Gender | Male | 34 (17) | Ref. | - | 42 (22) | Ref. | - |
Female | 22 (15) | 0.9 (0.5–1.4) | 0.56 | 27 (18) | 0.9 (0.6–1.3) | 0.4 | |
Type of acquisition | Community | 22 (15) | Ref | - | 29 (19) | Ref. | - |
HCA | 34 (18) | 1.2 (0.7–2.0) | 0.47 | 41 (21) | 1.1 (0.7–1.7) | 0.7 | |
Type of hospital | Tertiary | 38 (15) | Ref. | - | 51 (20) | Ref. | - |
Community | 18 (21) | 1.4 (0.8–2.3) | 0.2 | 19 (22) | 1.1 (0.7–1.7) | 0.7 | |
Neutropenia | No | 49 (15) | Ref. | - | 61 (19) | Ref. | - |
Yes | 7 (47) | 3.1 (1.7–5.6) | 0.001 | 9 (60) | 3.2 (2.0–5.1) | <0.001 | |
ICU admission | No | 46 (14) | Ref. | - | 61 (13) | Ref. | - |
Yes | 10 (45.5) | 3.1 (1.9–5.4) | <0.001 | 9 (41) | 2.1 (1.2–3.7) | 0.01 | |
Severity of SISR | Sepsis | 19 (7.8) | Ref. | - | 325 (13.1) | Ref. | - |
Severe sepsis or shock | 37 (38.5) | 5.0 (3.0-8.3) | <0.001 | 38/54 (39.6) | 3.03 (2.0–4.5) | <0.001 | |
Source of bacteremia | Vascular catheter | 1 (4) | Ref. | - | 2 (8) | Ref. | - |
Urinary tract | 7 (8) | 1.9 (0.2–14.9) | 0.5 | 9 (10) | 1.3 (0.2–9.2) | 1 | |
Intraabdominal | 12 (18) | 4.1 (0.6–29.6) | 0.1 | 17 (24) | 2.9 (0.7–11.5) | 0.1 | |
Other source | 9 (21) | 4.9 (0.7–36.5) | 0.1 | 10 (23) | 2.7 (0.7–11.4) | 0.2 | |
Unknown | 15 (23) | 5.5 (0.8–39.7) | 0.1 | 19 (29) | 4.5 (0.9–30.1) | 0.1 | |
Respiratory tract | 12 (25) | 6.0 (0.8–43.5) | 0.05 | 13 (27) | 3.2 (0.8–13.2) | 0.1 | |
Etiology | CONS | 1 (4) | Ref. | - | 2 (8) | Ref. | - |
K. pneumoniae | 2 (8) | 2.0 (0.2–20.6) | 1 | 4/(17) | 2.0 (0.4-) | 0.7 | |
E. coli | 13 (10.5) | 2.5 (0.3–18.3) | 0.5 | 17 (14) | 1.7 (0.4–6.7) | 0.7 | |
S. aureus | 7 (22) | 5.2 (0.7–39.9) | 0.1 | 8 (25) | 3.0 (0.7-12.9) | 0.2 | |
S. pneumoniae | 8 (22) | 5.3 (0.7–39.9) | 0.1 | 10 (28) | 3.3 (0.8–13.9) | 0.1 | |
Enterococcus spp. | 3 (23) | 5.5 (0.7–48.0) | 0.1 | 3 (23) | 2.8 (0.5–14.5) | 0.2 | |
Enterobacter spp | 2 (22) | 5.3 (0.5–1.9) | 0.2 | 3 (33) | 4.0 (0.8–20.1) | 0.1 | |
P. aeruginosa | 5 (36) | 8.6 (1.1–66.1) | 0.02 | 6 (43) | 5.1 (1.2–22.1) | 0.03 | |
Empirical therapy | Adequate | 40 (14) | Ref. | - | 53 (19) | Ref. | - |
Inadequate | 16 (28) | 2.0 (1.2–3.3) | 0.01 | 17 (30) | 1.6 (1.0–2.5) | 0.1 |