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Table 2 Genotype distributions of SNPs used in this study

From: Addition of host genetic variants in a prediction rule for post meningitis hearing loss in childhood: a model updating study

Genetic variables Total * Wildtype Heterozygous Mutant
  N % N % n % n %
TLR2-16934 T > A HL 32 94.1 7 21.9 15 46.9 10 31.3
TLR2-16934 T > A no HL 411 94.1 114 27.7 196 47.7 101 24.6
TLR2 + 2477 G > A HL 34 100 34 100 0 0 0 0
TLR2 + 2477 G > A no HL 430 98.4 382 88.8 46 10.7 2 0,5
TLR4 + 896 A > G HL 34 100 25 73.5 8 23.5 1 2.9
TLR4 + 896 A > G no HL 420 96.1 374 89.0 33 7.9 13 3.1
TLR9-1237 T > C HL 33 97.1 21 63.6 12 36.4 0 0
TLR9-1237 T > C no HL 430 98.4 320 74.4 101 23.5 9 2.1
TLR9 + 2848 G > A HL 33 97.1 5 15.2 16 48.5 12 36.4
TLR9 + 2848 G > A no HL 426 97.5 104 24.4 199 46.7 123 28.9
NOD1 + 32556 T > GG HL 34 100 20 58.8 13 38.2 1 2.9
NOD1 + 32556 T > GG no HL 414 94.7 239 57.7 148 35.7 27 6.5
NOD2 +2209 C > T HL 34 100 32 94.1 2 5.9 0 0
NOD2 +2209 C > T no HL 427 97.7 381 89.2 38 8.9 8 1.9
NOD2 +2722 G > C HL 31 91.2 31 100 0 0 0 0
NOD2 +2722 G > C no HL 421 96.3 410 97.4 8 1.9 3 0.7
NOD2 +3020 ins C HL 33 97.1 31 93.9 2 6.1 0 0
NOD2 +3020 ins C no HL 426 97.5 409 96.0 16 3.8 1 0.2
CASP1 + 8404 A > G HL 34 100 22 64.7 10 29.4 2 5.9
CASP1 + 8404 A > G no HL 433 99.11 258 59.6 145 33.5 30 6.9
TRAIL-692 T > C HL 33 97.1 26 78.8 6 18.2 1 3.0
TRAIL-692 T > C no HL 420 96.1 339 80.7 72 17.1 9 2.1
  1. *Genotypes and percentage of all included cases.
  2. Abbreviations:
  3. TLR: Toll-like receptor.
  4. HL: Hearing loss.
  5. NOD: Nucleotide oligomerization domain protein.
  6. CASP: Caspase.
  7. TRAIL: Tumour necrosis factor related apoptosis inducing ligand.