Effect of six rounds of mass drug administration (MDA) on circulating filarial antigen (CFA) prevalence. Brown line = volunteers from mosquito collection houses located in all four hamlets of Kirare examined for CFA by ELISA in survey 1-5. Green line = all individuals ≥ 1 year from two hamlets of Kirare (Mtambuuni, Mashine) examined for CFA by ICT cards in survey 7 and 8. Red lines = all individuals ≥ 1 year from one hamlet of Kiomoni (Mabavu) and one hamlet of Kisimatui (Majengo) examined for CFA by ICT cards in survey 7 and 8. Vertical stippled lines indicate rounds of MDA.