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Table 3 RSV-related hospitalization risk

From: Association of RSV-related hospitalization and non-compliance with Palivizumab among commercially insured infants: a retrospective claims analysis

Variable Post-index (Cox)
  Hazard ratio (95% CI) P-value*
Palivizumab non-compliance (ref. compliance) 2.007 (1.392 - 2.894) <0.001
Chronic lung disease 2.035 (1.262 - 3.281) 0.004
Congenital heart disease 1.24 (0.778 - 1.978) 0.366
33-36 wGA (ref. < 33 wGA) 0.983 (0.634 - 1.522) 0.937
Unknown wGA (ref. < 33 wGA) 1.966 (1.206 - 3.206) 0.007
Male gender (ref. female) 1.152 (0.841 - 1.578) 0.378
Geographic region – Northeast (ref. South) 0.813 (0.469 - 1.407) 0.459
Geographic region – Midwest (ref. South) 1.226 (0.854 - 1.759) 0.269
Geographic region – West (ref. South) 0.862 (0.526 - 1.414) 0.557
Index year – 2004 (ref. 2003) 1.027 (0.618 - 1.706) 0.919
Index year – 2005 (ref. 2003) 0.893 (0.528 - 1.513) 0.675
Index year – 2006 (ref. 2003) 0.724 (0.415 - 1.262) 0.254
Index year – 2007 (ref. 2003) 0.827 (0.463 - 1.476) 0.520
Index year – 2008 (ref. 2003) 0.922 (0.534 - 1.591) 0.769
Birth number – multiple birth (ref. single birth) 0.418 (0.267 - 0.655) <0.001
Birth number – unknown (ref. single birth) 0.656 (0.313 - 1.373) 0.263
Pre-index palivizumab use 0.507 (0.276 - 0.933) 0.029
NICU hospitalization at birth (ref. no NICU) 1.354 (0.807 - 2.274) 0.251
Unknown NICU hospitalization at birth (ref. no NICU) 0.875 (0.312 - 2.457) 0.800
Pre-index ambulatory visit 0.677 (0.162 - 2.827) 0.593
Pre-index emergency department visit 1.746 (1.231 - 2.477) 0.002
Pre-index inpatient hospitalization 1.258 (0.387 - 4.085) 0.703
Pre-index RSV-related hospitalization 3.059 (1.574 - 5.942) 0.001
Any pre-index comorbid condition 2.003 (1.411 - 2.843) <0.001
Low birth weight (<2500 g) 0.906 (0.598 - 1.373) 0.643
Birth month: May (ref. Sept) 1.019 (0.587 - 1.769) 0.947
Birth month: June (ref. Sept) 0.7 (0.394 - 1.244) 0.224
Birth month: July (ref. Sept) 0.794 (0.456 - 1.384) 0.416
Birth month: August (ref. Sept) 0.713 (0.405 - 1.256) 0.242
  1. *Values that reflect statistical significance at P<0.05 are in boldface.
  2. CI, Confidence interval.