Figure 4

Results of quantitative PCR of mRNA levels of OXA-72 in Acinetobacter baumannii carrying bla _OXA-72 in response to different antibiotics. The A. baumannii isolate carrying bla _OXA-72 was treated without antibiotics (Luria-Bertani broth, LB), or with ciprofloxacin (CIP) at 0.25 mg/L, ticarcillin (TIC) at 1024 mg/L, and imipenem (IMP) at 8 mg/L for 7 hours. Quantitative PCR revealed higher mRNA levels of OXA-72 in isolates treated with imipenem compared to those treated with ciprofloxacin or ticarcillin. * P value < 0.05 by one-way analysis of variance (ANOVA) and by the Scheffe post-hoc method.