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Table 1 Demographic, virological and immunological data for the entire population and the R5 and X4 subgroups, as identified by genotyping at T1

From: A stable CC-chemokine receptor (CCR)-5 tropic virus is correlated with the persistence of HIV RNA at less than 2.5 copies in successfully treated naïve subjects

 

All patients

R5 subgroup patients

X4 subgroup patients

p

Number

219

146

73

ns

Male (n)

173

118

55

ns

Italian (n)

180

114

66

ns

Agea (years)

41 (19–79)

40 (19–74)

43 (21–79)

p= 0.0332

Risk b

    

Heterosexual (n)

91

60

31

ns

MSM (n)

67

47

20

ns

Drug user (n)

18

11

7

ns

Missing (n)

43

28

15

ns

Subtype-B (n)

171

113

56

ns

Primarycn (%)

29 (13.2%)

21 (14.3%)

8 (11%)

Ns

T0 CD4 cells/mm3a

260 (0–1090)

284 (0–810)

201 (7–1090)

p= 0.0216

T0 CD4%a

16 (0–39)

17 (0–37)

13 (1–39)

ns

T0 HIV RNAa copies/ml

101836 (412–1x107)

101836 (412–1x107)

1000182 (547–6258236)

ns

T0 HIV DNAa, d

1198 (33–70123)

1185 (70–18856)

1297 (33–70123)

ns

T1 CD4 cells/mm3a

560 (54–1330)

580 (54–1306)

485 (96–1330)

ns

T1 CD4%a

28.9 (3.4–55.2)

29.9 (3.4–55,2)

26 (5–51.9)

ns

T1 HIV RNA<2,5 copies/ml n (%)

83 (37.9%)

62 (42.4%)

21 (28.7%)

ns

T1 HIV DNAa, d

107 (5–892)

105 (5–892)

110 (5–740)

ns

  1. aExpressed as median and range.
  2. bTransmission risk reported as prevalent.
  3. c Being in HIV Primary Infection at the start of therapy.
  4. d Copies/106PBMCs.