(+) Serums
|
R1
|
R2
|
R3
|
R4
|
---|
DENV1
|
0.94 ± 0.05
|
0.83 ± 0.06
|
0.64 ± 0.08
|
0.59 ± 0.08
|
DENV2
|
0.90 ± 0.03
|
0.88 ± 0.05
|
0.57 ± 0.06
|
0.42 ± 0.07
|
DENV3
|
0.82 ± 0.06
|
0.75 ± 0.07
|
0.77 ± 0.07
|
0.18 ± 0.08
|
DENV4
|
0.73 ± 0.05
|
0.55 ± 0.06
|
0.45 ± 0.06
|
0.61 ± 0.07
|
DENV1-4
|
0.83 ± 0.03
|
0.73 ± 0.04
|
0.59 ± 0.04
|
0.47 ± 0.04
|
- R1 to R4, (H6-ED3-PhoA)2 dimers of serotypes DENV1 to DENV4, respectively. The first column gives the serotype of the infecting DENV for the (+) serums. DENV1-4, the serotype of the infecting virus could be any one of DENV1 to DENV4. The DENV-uninfected serums were always taken as (−) serums. Each entry gives the accuracy and associated standard error of a MAC-ELISA that used the Ri reagent (i = 1, …, 4) as an antigen and was evaluated on the (+) and (−) serums.