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Table 1 Blood culture results

From: Ambulatory consolidation chemotherapy for acute myeloid leukemia with antibacterial prophylaxis is associated with frequent bacteremia and the emergence of fluoroquinolone resistant E. Coli

 

C#1

C#2

(p-value)

Total Number of Patients

196

187

 

Age < 60

140

126

 

Age ≥ 60

56

61

 

% Male

107 (54.6%)

98 (52.3%)

 

At least one blood culture positive (% of patients)

43 (21.9%)

59 (31.6%)

P=0.03

1 culture positive

37 (86%)

53 (90%)

NS

2 or more cultures positive

6 (14%)

6 (10%)

NS

Patients with Gram Positive isolates (% of Patients)

35 (17.9%)

46 (24.6%)

0.11

Patients with Gram Negative isolates (% of patients)

11 (5.6%)

20 (10.7%)

0.07

Gram Positive vs. Gram Negative

P=0.0002

P=0.0004

 

Total number of positive blood cultures:

49

65

 

Monomicrobial cultures (% of total cultures)

45 (91.8%)

60 (92.3%)

NS

Polymicrobial cultures (% of total cultures)

4 (8.2%)

5 (7.7%)

NS

Total number of isolates:

53

71

 

Age < 60

40

44

 

Age ≥ 60

13

27

 

Clinical Isolates (% of patients)

   

Gram Positive +

35 (17.9%)

46 (24.6%)

P=0.10

CNST*

19 (9.7%)

23 (12.4%)

NS

Corynebacterium

5 (2.6%)

2 (1.1%)

 

Micrococcus

4 (2.0%)

  

Enterococcus

1 (0.5%)

3 (1.6%)

 

Staphyloccoccus. aureus

2 (1.0%)

1 (0.5%)

 

Streptococcus species

9 (4.6%)

16 (8.6%)

P=0.11

Streptococcus viridins

6 (3.1%)

13 (7.0%)

 

Streptococcus viridians/Streptococcus oralis

-

1 (0.5%)

 

Streptococcus mitis

2 (1.0%)

-

 

Streptococcus auralis

-

1 (0.5%)

 

Streptococcus spp.

1 (0.5%)

1 (0.5%)

 

< age 60 with Strep.

6 (4.3%)

14 (11.2%)

P=0.033

≥ age 60 with Strep.

3 (5.36%)

2 (3.3%)

NS

Other Gram Positive

1 (0.5%)

4 (2.1%)

 

Gram Negative

11 (5.6%)

20 (10.7%)

P=0.07

Age < 60

8 (5.7%)

9 (7.1%)

NS

Age ≥ 60

3 (5.4%)

11 (18%)

P=0.035

Eschericia coli

1 (0.5%)

10 (5.3%)

P=0.005

Klebsiella

2 (1.0%)

5 (2.7%)

 

Enterobacter

3 (1.5%)

1 (0.5%)

 

Pseudomonas spp.

4 (2.0%)

-

 

Other Gram Negative

1 (0.5%)

4 (2.1%)

 

Yeast

-

1 (0.5%)

 
  1. CNST* = coagulase-negative staphylococci;
  2. Gram Positive+ = Species information available for 185 pts. in C2 (Age < 60=125, Age ≥ 60=65).