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Table 3 Mutation patterns of eight isolates of M. tuberculosis

From: Resistance of Mycobacterium tuberculosis to antibiotics in Lao PDR: first multicentric study conducted in 3 hospitals

Patient number (hospital)

Previously treated case

Mutations conferring resistance to

INH

RMP

FLQ

AG/CP

EMB

425 (LP)

No

katG S315T

-

-

-

-

inhA C15T

472 (TK)

No

inhA C15T

-

-

-

-

977 (MV)

No

katG S315T

-

-

-

-

454 (MV)

Yes

katG S315T

-

-

-

-

446 (LP)

No

inhA C15T

-

-

rrs C1402T

-

480 (TK)

No

katG S315T

-

-

rrs C1402T

-

165 (LP)

Yes

katG deleted

-

-

rrs C1402T

-

175 (TK)

Yes

katG S315T

rpoB H526Y

gyrA A90V

rrs C1402T

embB M306V

Total

8

1

1

4

1

  1. LP Luang Prabang, MV Mahosot Vientiane, TK Thakhek, INH isionazid, RMP rifampycin, FLQ fluoroquinolones, AG/CP aminoglycosides, cyclic peptides, EMB ethambutol.
  2. (−) Presence of all wild type probes and none mutation probe observed.