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Table 6 Multivariate model of factors related to the presence of subclinical atherosclerosis among 361 individuals without the main risk factors for cardiovascular disease (CVD) (excluding a total of 333 patients = 166 patients with metabolic syndrome, 20 obese patients, 77 hypertensive patients, 24 individuals with total cholesterol ≥ 240 mg /dL and 46 smokers) (Model A) and among 333 patients with risk factors for cardiovascular diseases (Model B)

From: Risk factors for subclinical atherosclerosis in HIV-infected patients under and over 40 years: a case–control study

Variables Multivariate Model A (n=361) Multivariate Model B (n=333)
< 40 years old (n=218) ≥ 40 years old (n=143) < 40 years old (n=133) ≥ 40 years old (n=200)
OR(CI) p-value OR(CI) p-value OR(CI) p-value OR(CI) p-value
Age (continuous) 1.09 (1.00 – 1.19) 0.037 1.15 (1.06 – 1.25) 0.000 1.21 (1.08 – 1.36) 0.001 1.12 (1.04 – 1.21) 0.003
Male sex 3.02 (1.20 – 7.59) 0.018 1.03 (0.45 – 2.34) 0.937 1.59 (0.64 – 3.95) 0.311 2.53 (1.16 – 5.51) 0.019
Nonwhite race 3.21 (0.90 – 11.4) 0.071 1.23 (0.42 – 3.67) 0.702 2.59 (0.96 – 6.99) 0.060 1.28 (0.55 - 2.99) 0.557
Stable partner 1.62 (0.64 – 4.08) 0.306 3.97 (1.46 – 10.8) 0.007 3.14 (1.13 – 8.72) 0.028 2.04 (0.78 – 5.36) 0.144
CD4+ T-lymphocytes <200 1.0   1.0   1.0   1.0  
200 to < 350 cels/mm3 1.07 (0.35 – 3.23) 0.902 0.97 (0.34 – 2.79) 0.967 0.51 (0.07 – 3.38) 0.486 2.52 (0.85 – 7.48) 0.094
≥ 350 cels/mm3 0.49 (0.12 – 1.98) 0.321 2.41 (0.68 – 8.47) 0.168 0.82 (0.11 – 5.79) 0.847 10.8 (2.89 – 40.4) 0.000
Undetectable Viral Load 1.0   1.0   1.0   1.0  
50 to < 10,000 0.96 (0.24 – 3.78) 0.954 2.16 (0.50 – 9.37) 0.300 0.48 (0.09 – 2.40) 0.378 0.54 (0.15 – 1.98) 0.355
10,000 to < 100,000 0.47 (0.07 – 2.93) 0.425 5.95 (1.00 – 35.3) 0.050 0.83 (0.11 – 6.28) 0.863 1.46 (0.23 – 9.11) 0.681
≥ 100,000 0.33 (0.02 – 4.08) 0.394 6.84 (0.90 – 51.8) 0.063 0.27 (0.00 –12.77) 0.512 0.91 (0.10 - 7.80) 0.933
HAART duration of use         
No HAART use 1.0   1.0   1.0   1.0  
IP < 5 years 0.51 (0.15 – 1.75) 0.290 0.47 (0.137 – 1.66) 0.245 0.75 (0.19 – 2.87) 0.682 1.72 (0.60 – 4.89) 0.307
IP ≥ 5 years - - 3.62 (0.48 – 26.8) 0.208 0.87 (0.05-15.65) 0.925 -  
NNRTI < 5 years 0.55 (0.18 – 1.62) 0.281 1.79 (0.57 – 5.59) 0.316 2.84 (0.92-8.68) 0.067 2.01 (0.71 – 5.71) 0.189
NNRTI ≥ 5 years 2.41 (0.59 – 9.82) 0.218 7.60 (1.61 – 35.8) 0.010 0.24 (0.02-2.53) 0.236 2.04 (0.63 - 6.58) 0.229