Table 6 Multivariate model of factors related to the presence of subclinical atherosclerosis among 361 individuals without the main risk factors for cardiovascular disease (CVD) (excluding a total of 333 patients = 166 patients with metabolic syndrome, 20 obese patients, 77 hypertensive patients, 24 individuals with total cholesterol ≥ 240 mg /dL and 46 smokers) (Model A) and among 333 patients with risk factors for cardiovascular diseases (Model B)
Variables | Multivariate Model A (n=361) | Multivariate Model B (n=333) | ||||||
|---|---|---|---|---|---|---|---|---|
< 40 years old (n=218) | ≥ 40 years old (n=143) | < 40 years old (n=133) | ≥ 40 years old (n=200) | |||||
OR(CI) | p-value | OR(CI) | p-value | OR(CI) | p-value | OR(CI) | p-value | |
Age (continuous) | 1.09 (1.00 – 1.19) | 0.037 | 1.15 (1.06 – 1.25) | 0.000 | 1.21 (1.08 – 1.36) | 0.001 | 1.12 (1.04 – 1.21) | 0.003 |
Male sex | 3.02 (1.20 – 7.59) | 0.018 | 1.03 (0.45 – 2.34) | 0.937 | 1.59 (0.64 – 3.95) | 0.311 | 2.53 (1.16 – 5.51) | 0.019 |
Nonwhite race | 3.21 (0.90 – 11.4) | 0.071 | 1.23 (0.42 – 3.67) | 0.702 | 2.59 (0.96 – 6.99) | 0.060 | 1.28 (0.55 - 2.99) | 0.557 |
Stable partner | 1.62 (0.64 – 4.08) | 0.306 | 3.97 (1.46 – 10.8) | 0.007 | 3.14 (1.13 – 8.72) | 0.028 | 2.04 (0.78 – 5.36) | 0.144 |
CD4+ T-lymphocytes <200 | 1.0 | 1.0 | 1.0 | 1.0 | ||||
200 to < 350 cels/mm3 | 1.07 (0.35 – 3.23) | 0.902 | 0.97 (0.34 – 2.79) | 0.967 | 0.51 (0.07 – 3.38) | 0.486 | 2.52 (0.85 – 7.48) | 0.094 |
≥ 350 cels/mm3 | 0.49 (0.12 – 1.98) | 0.321 | 2.41 (0.68 – 8.47) | 0.168 | 0.82 (0.11 – 5.79) | 0.847 | 10.8 (2.89 – 40.4) | 0.000 |
Undetectable Viral Load | 1.0 | 1.0 | 1.0 | 1.0 | ||||
50 to < 10,000 | 0.96 (0.24 – 3.78) | 0.954 | 2.16 (0.50 – 9.37) | 0.300 | 0.48 (0.09 – 2.40) | 0.378 | 0.54 (0.15 – 1.98) | 0.355 |
10,000 to < 100,000 | 0.47 (0.07 – 2.93) | 0.425 | 5.95 (1.00 – 35.3) | 0.050 | 0.83 (0.11 – 6.28) | 0.863 | 1.46 (0.23 – 9.11) | 0.681 |
≥ 100,000 | 0.33 (0.02 – 4.08) | 0.394 | 6.84 (0.90 – 51.8) | 0.063 | 0.27 (0.00 –12.77) | 0.512 | 0.91 (0.10 - 7.80) | 0.933 |
HAART duration of use | ||||||||
No HAART use | 1.0 | 1.0 | 1.0 | 1.0 | ||||
IP < 5 years | 0.51 (0.15 – 1.75) | 0.290 | 0.47 (0.137 – 1.66) | 0.245 | 0.75 (0.19 – 2.87) | 0.682 | 1.72 (0.60 – 4.89) | 0.307 |
IP ≥ 5 years | - | - | 3.62 (0.48 – 26.8) | 0.208 | 0.87 (0.05-15.65) | 0.925 | - | |
NNRTI < 5 years | 0.55 (0.18 – 1.62) | 0.281 | 1.79 (0.57 – 5.59) | 0.316 | 2.84 (0.92-8.68) | 0.067 | 2.01 (0.71 – 5.71) | 0.189 |
NNRTI ≥ 5 years | 2.41 (0.59 – 9.82) | 0.218 | 7.60 (1.61 – 35.8) | 0.010 | 0.24 (0.02-2.53) | 0.236 | 2.04 (0.63 - 6.58) | 0.229 |