Variables | < 40 years (n=351) | ≥ 40 years (n=346) | p-value |
---|---|---|---|
Sociodemographics | |||
Age (years) – Mean (SD) | 31.8 (4.96) | 47.8 (6.14) | < 0.001 |
Male (%) | 59.5 | 57.8 | 0.641 |
White (%) | 25.6 | 24.9 | 0.811 |
Stable partner (%) | 19.4 | 24.3 | 0.117 |
Habits | |||
Smoking (%) | 23.0 | 22.0 | 0.725 |
Alcohol consumption (%) | 40.4 | 35.2 | 0.167 |
Injecting drugs use (%) | 6.0 | 3.8 | 0.368 |
Clinical characteristics | |||
Diabetes (%) | 0.9 | 6.2 | < 0.001 |
Lipodystrophy (%) | 31.5 | 39.8 | 0.024 |
Dyslipidemia (%) | 16.1 | 31.7 | < 0.001 |
Metabolic syndrome (%) | 16.9 | 31.3 | < 0.001 |
HIV-related characteristics | |||
Time elapsed since diagnosis HIV (in months -DP) | 40.5 (37.5) | 58.4 (49.6) | < 0.001 |
CD4 T-lymphocytes baseline - Median (P25 – P75) | 323 (158 – 498) | 258 (94 – 473) | 0.005* |
Viral load baseline - Median (P25 – P75) | 29600 (3341 – 134000) | 57400 (6170 – 205000) | 0.026* |
CD4 T-lymphocytes current - Median (P25 – P75) | 391 (262 – 535) | 383 (242 – 564) | 0.949* |
Viral load, current undetectable (%)** | 31.7 | 46.7 | 0.005 |
HAART duration (in months) Median (P25–P75) | 23.5 (9.9 – 42.6) | 36.3 (17.7 – 65.2) | < 0.001* |
NNTRI Use (%) | 36.6 | 47.1 | 0.005 |
PI use (%) | 21.7 | 26.9 | 0.112 |
Without HAART (%) | 41.3 | 25.7 | < 0.001 |
Laboratory tests | |||
Total cholesterol (mg/dL) - Mean (SD) | 163.5 (40.0) | 189.6 (54.5) | < 0.001 |
LDL cholesterol (mg/dL) - Mean (SD) | 93.9 (38.8) | 106.7 (40.8) | 0.001 |
HDL cholesterol (mg/dL) - Mean (SD) | 42.2 (13.6) | 43.5 (14.1) | 0.216 |
Triglycerides (mg/dL) - Mean (SD) | 148.8 (102.8) | 204.6 (213.0) | < 0.001 |
USG of carotid arteries | |||
Presence of sublinical atherosclerosis (%) | 23.4 | 66.5 | < 0.001 |
Carotid intima thickness (mm) - Median (SD) | 0.742 (0.084) | 0.841 (0.150) | < 0.001 |