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Table 1 Comparison of qualitative and quantitative variables in HIV-infected individuals according to age group, followed in two referral hospitals in the state of Pernambuco, Brazil

From: Risk factors for subclinical atherosclerosis in HIV-infected patients under and over 40 years: a case–control study

Variables < 40 years (n=351) ≥ 40 years (n=346) p-value
Sociodemographics    
Age (years) – Mean (SD) 31.8 (4.96) 47.8 (6.14) < 0.001
Male (%) 59.5 57.8 0.641
White (%) 25.6 24.9 0.811
Stable partner (%) 19.4 24.3 0.117
Habits    
Smoking (%) 23.0 22.0 0.725
Alcohol consumption (%) 40.4 35.2 0.167
Injecting drugs use (%) 6.0 3.8 0.368
Clinical characteristics    
Diabetes (%) 0.9 6.2 < 0.001
Lipodystrophy (%) 31.5 39.8 0.024
Dyslipidemia (%) 16.1 31.7 < 0.001
Metabolic syndrome (%) 16.9 31.3 < 0.001
HIV-related characteristics    
Time elapsed since diagnosis HIV (in months -DP) 40.5 (37.5) 58.4 (49.6) < 0.001
CD4 T-lymphocytes baseline - Median (P25 – P75) 323 (158 – 498) 258 (94 – 473) 0.005*
Viral load baseline - Median (P25 – P75) 29600 (3341 – 134000) 57400 (6170 – 205000) 0.026*
CD4 T-lymphocytes current - Median (P25 – P75) 391 (262 – 535) 383 (242 – 564) 0.949*
Viral load, current undetectable (%)** 31.7 46.7 0.005
HAART duration (in months) Median (P25–P75) 23.5 (9.9 – 42.6) 36.3 (17.7 – 65.2) < 0.001*
NNTRI Use (%) 36.6 47.1 0.005
PI use (%) 21.7 26.9 0.112
Without HAART (%) 41.3 25.7 < 0.001
Laboratory tests    
Total cholesterol (mg/dL) - Mean (SD) 163.5 (40.0) 189.6 (54.5) < 0.001
LDL cholesterol (mg/dL) - Mean (SD) 93.9 (38.8) 106.7 (40.8) 0.001
HDL cholesterol (mg/dL) - Mean (SD) 42.2 (13.6) 43.5 (14.1) 0.216
Triglycerides (mg/dL) - Mean (SD) 148.8 (102.8) 204.6 (213.0) < 0.001
USG of carotid arteries    
Presence of sublinical atherosclerosis (%) 23.4 66.5 < 0.001
Carotid intima thickness (mm) - Median (SD) 0.742 (0.084) 0.841 (0.150) < 0.001
  1. * Kruskal - Wallis test.
  2. ** 328 patients with viral load information.