Table 1 Patients characteristics
From: Inflammatory parameters and prediction of prognosis in infective endocarditis
Characteristic | Total (n = 50) | Adverse event (n = 27) | Event-free survival (n = 23) | p-value |
|---|---|---|---|---|
Age, (years ± SD) | 57 ± 17 | 52 ± 16 | 62 ± 16 | |
Male / Female (n) | 36 / 14 | 18 / 9 | 18 / 5 | |
Charlson Comorbidity Score age adjusted | ||||
(Median, interquartile range) | 1 [0 – 4] | 1 [0 – 4] | 0 [0 – 4,5] | 0.89 |
Diabetes Mellitus (n) | 8 | 6 | 2 | 0.19 |
Immunocompromised* (n) | 1 | 1 | 0 | -- |
i.v. Drug Abuse (n) | 6 | 6 | 0 | 0.02 |
Conditions at diagnosis (n) | ||||
Vasopressors | 15 | 12 | 3 | 0.02 |
Mechanical ventilation | 11 | 8 | 3 | 0.16 |
ICU | 17 | 12 | 5 | 0.09 |
Site of infection (n, %) | ||||
Aortic valve | 29 (58%) | 13 | 16 | 0.58 |
Pulmonary valve | 1 (2%) | 1 | 0 | -- |
Mitral valve | 14 (28%) | 8 | 6 | 0.59 |
Tricuspid valve | 6 (12%) | 5 | 1 | -- |
Prosthetic valve (n) | 11 | 8 | 3 | 0.16 |
Known valvular disease (n) | 13 | 7 | 6 | 1 |
Echocardiography | ||||
Perivalvular abscedation (n) | 5 | 4 | 1 | 0.22 |
Severe Insufficiency (n) | 21 | 8 | 13 | 0.05 |
Size of vegetation | ||||
(2D, mm2, median, interquartile range) | 103 [32 – 179] | 105 [54 – 195] | 98 [27 – 162] | 0.22 |
Causative organism (n, %) | ||||
Staphylococcus aureus | 16 (32%) | 15 | 1 | < 0.01 |
Staphylococci other than aureus | 7 (14%) | 2 | 0 | -- |
B-Streptococci | 2 (4%) | 0 | 2 | -- |
Streptococci other than B | 11 (22%) | 2 | 9 | 0.03 |
Enterococcus faecium | 5 (10%) | 2 | 3 | -- |
Actinomyces israelii | 1 (2%) | 0 | 1 | -- |
No proven causative organism | 7 (14%) | 4 | 0 | -- |