Table 1 Baseline patient demographics, characteristics, and medical history
FPV/r + ABC/3TC (n = 51) | EFV + ABC/3TC (n = 50) | |
|---|---|---|
Median age, years (range) | 34.0 (18–79) | 33.5 (19–55) |
Female, n (%) | 16 (31%) | 16 (32%) |
Race/ethnicity, n (%) | ||
African American, non-Hispanic | 29 (57%) | 33 (66%) |
Hispanic, non-African American | 18 (35%) | 13 (26%) |
African American and Hispanic | 3 (6%) | 4 (8%) |
Asian | 1 (2%) | 0 |
Median plasma HIV-1 RNA, log10 copies/mL | 4.96 | 4.82 |
≥100,000 copies/mL, n (%) | 22 (43%) | 20 (40%) |
Median CD4 cell count, cells/mm3 (range) | 237.0 (19–1061) | 272.5 (19–699) |
<200 cells/mm3, n (%) | 21 (41%) | 17 (34%) |
<50 cells/mm3, n (%) | 3 (6%) | 7 (14%) |
Positive hepatitis C serology | 5 (10%) | 5 (10%) |
CDC classification for HIV infection, n (%) | ||
Category A | 40 (78%) | 43 (86%) |
Category B | 4 (8%) | 7 (14%) |
Category C | 7 (14%) | 0 |
Framingham risk score <5%*, n (%) | 28 (78%) | 28 (88%) |
Diabetes type II, n (%) | 3 (6%) | 1 (2%) |
Hypercholesterolemia, n (%) | 17 (33%) | 14 (28%) |
Hypertension, n (%) | 9 (18%) | 12 (24%) |
Tobacco use | ||
Never smoked, n (%) | 26 (51%) | 19 (38%) |
Current smoker, n (%) | 20 (39%) | 20 (40%) |
Former smoker, n (%) | 5 (10%) | 11 (22%) |
Years smoked, median (range)† | 10 (2–39) | 10 (0–33) |