TY - JOUR AU - Graham, Susan M. AU - Rajwans, Nimerta AU - Tapia, Kenneth A. AU - Jaoko, Walter AU - Estambale, Benson BA AU - McClelland, R. Scott AU - Overbaugh, Julie AU - Liles, W. Conrad PY - 2013 DA - 2013/06/04 TI - A prospective study of endothelial activation biomarkers, including plasma angiopoietin-1 and angiopoietin-2, in Kenyan women initiating antiretroviral therapy JO - BMC Infectious Diseases SP - 263 VL - 13 IS - 1 AB - HIV-1-related inflammation is associated with increased levels of biomarkers of vascular adhesion and endothelial activation, and may increase production of the inflammatory protein angiopoietin-2 (ANG-2), an adverse prognostic biomarker in severe systemic infection. We hypothesized that antiretroviral therapy (ART) initiation would decrease endothelial activation, reducing plasma levels of ANG-2. SN - 1471-2334 UR - https://doi.org/10.1186/1471-2334-13-263 DO - 10.1186/1471-2334-13-263 ID - Graham2013 ER -