Genotype | Neuropsychiatric disorders | p value | ||||
---|---|---|---|---|---|---|
 | No |  | Yes | |||
n | % | n | % | |||
CYP2B6*6 | *1/*1 | 21 | 42 | 61 | 44.5 | 0.16 |
*1/*6 | 28 | 56 | 63 | 46 | Â | |
*6/*6 | 1 | 2 | 13 | 9.5 | Â | |
CYP2B6*11 | *1/*1 | 41 | 82 | 111 | 78.2 | 0.17 |
*1/*11 | 8 | 16 | 31 | 21.8 | Â | |
*11/*11 | 1 | 2 | 0 | 0 | Â | |
CYP2A6*9 | *1/*1 | 39 | 84.8 | 98 | 79.7 | 0.51 |
*1/*9 | 7 | 15.2 | 22 | 17.9 | Â | |
*9/*9 | 0 | 0 | 3 | 2.4 | Â | |
CYP2A6*17 | *1/*1 | 38 | 90.5 | 104 | 83.9 | 0.3 |
*1/*17 | 3 | 7.1 | 19 | 15.3 | Â | |
*17/*17 | 1 | 2.4 | 1 | 0.8 | Â | |
No. of CYP3A5*1 allelesa | zero | 15 | 30 | 31 | 21.8 | 0.48 |
One | 24 | 48 | 79 | 55.6 | Â | |
Two | 11 | 22 | 32 | 22.5 | Â | |
ABCB1 (rs3842 | *0/*0 | 29 | 63 | 87 | 65.4 | 0.95 |
*0/*1 | 16 | 34.8 | 43 | 32.3 | Â | |
*1/*1 | 1 | 2.2 | 3 | 2.3 | Â | |
ABCB1 c.3435C/T | CC | 37 | 74 | 109 | 77.9 | 0.68 |
CT | 13 | 26 | 30 | 21.4 | Â | |
TT | 0 | 0 | 1 | 0.7 | Â | |
NR1I3 rs3003569CT | TT | 10 | 21.7 | 29 | 23 | 0.06 |
TC | 16 | 34.8 | 65 | 51.6 | Â | |
CC | 20 | 43.5 | 32 | 25.4 | Â | |
Alleles | Frequency (%) | Frequency (%) | Â | |||
CYP2B6*6 | 30 | 32.5 | 0.21 | |||
CYP2B6*11 | 10 | 10.9 | 0.78 | |||
CYP2A6*9 | 7.61 | 11.38 | 0.31 | |||
CYP2A6*17 | 5.95 | 8.46 | 0.55 | |||
No. of CYP3A5*1 allele | 46 | 50.4 | 0.56 | |||
ABCB1 rs3842 | 19.6 | 18.4 | 0.80 | |||
ABCB1 c.3435T | 13 | 11.4 | 0.67 | |||
NR1I3 rs3003569 T | 39.1 | 48.8 | 0.11 |