Table 5 Linear regression models for square-root transformed C _min and C _max

Age (per 10 years)

0.02

(−0.07 - 0.11)

0.62

0.00

(−0.04 - 0.05)

0.95

Race

   White

Reference

   Black

−0.16

(−0.35 - 0.03)

0.09

−0.06

(−0.16 - 0.04)

0.25

   Other

−0.20

(−0.50 - 0.11)

0.20

0.01

(−0.15 - 0.17)

0.91

Risk Factor

   IDU

−0.21

(−0.45 - 0.04)

0.10

−0.10

(−0.23 - 0.02)

0.10

   Endemic country

−0.08

(−0.26 - 0.10)

0.38

−0.07

(−0.16 - 0.02)

0.14

   Heterosexual contact

0.13

(−0.05 - 0.32)

0.16

0.07

(−0.03 - 0.16)

0.16

   Blood transfusion

−0.08

(−0.38 - 0.22)

0.60

−0.08

(−0.23 - 0.07)

0.31

   Unknown

−0.06

(−0.34 - 0.23)

0.69

0.01

(−0.14 - 0.15)

0.90

Years since HIV diagnosis (per 10 years)

0.00

(−0.00 - 0.00)

0.84

−0.00

(−0.00 - 0.00)

0.53

Baseline CD4 (per 100/μL)

0.02

(−0.02 - 0.06)

0.28

0.00

(−0.02 - 0.02)

0.97

Baseline CD4 > 200/μL

0.07

(−0.11 - 0.24)

0.46

0.03

(−0.06 - 0.12)

0.51

Current CD4 (per 100/μL)

0.04

( 0.00 - 0.08)

0.03

0.01

(−0.01 - 0.03)

0.61

Current CD4 > 200/μL

0.30

(−0.25 - 0.84)

0.28

0.16

(−0.12 - 0.44)

0.26

Baseline VL (log₁₀ copies/mL)

−0.02

(−0.09 - 0.06)

0.64

−0.00

(−0.04 - 0.03)

0.81

AIDS diagnosis

0.07

(−0.12 - 0.27)

0.46

0.06

(−0.04 - 0.16)

0.27

Years on current regimen

−0.01

(−0.05 - 0.03)

0.68

−0.00

(−0.02 - 0.02)

0.83

Hepatitis B co-infection

0.22

(−0.34 - 0.78)

0.44

−0.04

(−0.33 - 0.24)

0.76

Hepatitis C co-infection

0.18

(−0.07 - 0.44)

0.17

−0.10

(−0.23 - 0.03)

0.14

Smoking Status

   Smoker

Reference

   Previous Smoker

0.02

(−0.27 - 0.31)

0.89

0.05

(−0.10 - 0.20)

0.49

Never

−0.13

(−0.31 - 0.06)

0.18

0.02

(−0.08 - 0.11)

0.70

Hypertension

0.14

(−0.12 - 0.41)

0.28

0.02

(−0.12 - 0.15)

0.82

Diabetes

0.02

(−0.43 - 0.47)

0.94

−0.05

(−0.28 - 0.18)

0.66

Weight (per kg)

0.00

(−0.00 - 0.01)

0.36

0.00

(−0.00 - 0.00)

0.32

BMI (per kg/m²)

0.00

(−0.01 - 0.02)

0.47

0.00

(−0.00 - 0.01)

0.64

Menopausal (self-reported)

0.05

(−0.14 - 0.25)

0.59

0.03

(−0.07 - 0.14)

0.55