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Table 4 Positive rate and timing of anti-Eno and anti-Fba1 antibodies in non-neutropenic and neutropenic patients with candidemia [ n (%)]

From: Diagnostic value of immunoglobulin G antibodies against Candida enolase and fructose-bisphosphate aldolase for candidemia

Population (No. of subjects)

Anti-Eno

Anti-Fba1

Ab*(+) prior to BC(+)

BC**(+) prior to Ab(+)

Total

Ab(+) prior to BC(+)

BC(+) prior to Ab(+)

Total

Non-neutropenia (90)

38 (42.2)

31 (34.4)

69 (76.7)

46 (51.1)

37 (41.1)

83 (92.2)

Neutropenia# (11)

3 (27.3)

1 (9.1)

4 (36.4)a

4 (36.4)

1 (9.1)

5 (45.5)b

Total (101)

41 (40.6)

32 (31.7)

73 (72.3)

50 (49.5)

38 (37.6)

88 (87.1)

  1. *Ab: antibody, ** BC: blood culture.
  2. #Neutropenia was defined as an absolute neutrophil count below 500 cells/mm3.
  3. a P = 0.005, for the comparison with the Non-neutropenia group.
  4. b P < 0.001, for the comparison with the Non-neutropenia group.