Diagnostic value of immunoglobulin G antibodies against Candida enolase and fructose-bisphosphate aldolase for candidemia

Table 3 Diagnostic value of anti-Eno and anti-Fba1 on the test cohort

	Anti-Eno	Anti-Fba1	Combination of anti-Eno and anti-Fba1
True negative	354	347	339
False positive	20	27	35
True positive	73	88	91
False negative	28	13	10
Sensitivity (%)	72.3	87.1	90.1
Specificity (%)	94.7	92.8	90.6
Negative predictive value (%)	93.0	96.4	97.1
Positive predictive value (%)	78.5	76.5	72.2

The number of patients is presented in the upper part of the table. Sensitivity, specificity, and positive and negative predictive values are estimated in percentage calculated from patient responses. In the combined detection of anti-Eno and anti-Fba1, sera with single or both assay positive results were regarded as positive.

ISSN: 1471-2334