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Table 4 A-C: Spearman correlations between selected transcript signals and CD4 count, Nadir CD4 count, and viral load control group

From: MicroRNA regulation and its effects on cellular transcriptome in Human Immunodeficiency Virus-1 (HIV-1) infected individuals with distinct viral load and CD4 cell counts

   CD4 Count Nadir CD4   
(A) Control group Transcript Spearman r p-value Spearman r p-value   
CCL2 −0.00296 0.986 0.156 0.358   
CXCL5 0.0385 0.821 0.101 0.553   
IL6 −0.0236 0.877 0.0424 0.799   
IL8 0.0234 0.891 0.227 0.176   
NRGN −0.186 0.278 −0.172 0.309   
   CD4 Count Nadir CD4   
(B) LVL group Transcript Spearman r p-value Spearman r p-value   
CCL2 −0.281 0.133 −0.193 0.283   
CXCL5 0.025 0.895 −0.026 0.883   
IL6 −0.488 0.006* −0.185 0.304   
IL8 −0.219 0.246 −0.143 0.427   
NRGN 0.41 0.024* 0.314 0.074   
(C) HVL group   CD4 Count Nadir CD4 Viral load
Transcript Spearman r p-value Spearman r p-value Spearman r p-value
CCL2 −0.022 0.918 −0.084 0.695 0.202 0.355
CXCL5 −0.277 0.190 −0.367 0.078 0.190 0.385
IL6 −0.324 0.122 −0.414 0.044* −0.199 0.364
IL8 −0.495 0.014* −0.609 0.001** −0.085 0.670
NRGN 0.224 0.292 0.153 0.475 0.143 0.516
  1. Spearman correlations between selected transcripts and CD4 count, Nadir CD4 count, and viral load (where applicable) within the three study groups obtained from GraphPad Prism software set to produce two-tailed p-value. * = p < 0.05; ** = p < 0.001.