Network of predicted miRNA-mRNA interactions by GroupMiR using results from miRNA and mRNA array and visualized by Cytoscape. Regression-based method was used to predict the potential miRNA (circles) that actively regulate mRNA (squares). Selected miRNA (four) were chosen from a list of miRNAs and their targets. Red and green within the mRNA represents up and down regulation, respectively. Each slice within the circle represents HIV-1 infected subject.