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Table 4 Relative performance of Diagnostic tests for Leishmaniasis

From: Varied spectrum of clinical presentation and mortality in a prospective registry of visceral leishmaniasis in a low endemicity area of Northern Italy

 

I.F. Serology

Microscopy (BM)

Urinary Ag

PCR - P. Blood

PCR-Bone Marrow

Group (n°)

POS

NEG

ND

POS

NEG

ND

POS

NEG

ND

POS

NEG

ND

POS

NEG

ND

Children(19)

14 (73,6%)

1 (5.3%)

4

17 (89.5%)

1 (5.3%)

1

0

0

19

1 (5.3%)

0

18

8 (42.1%)

0

11

Adults(36)

33(91,7%)

2(5,6%)

1

19(52,8%)

4(11,1%)

13

25(69,5%)

3(8.3%)

8

5(13,9%)

2(5,6%)

29

3(8,4%)

0

33

ICC(17)

15(88,2%)

1(6,7%)

1

11(64,7%)

4(23,5%)

2

8(47.0%)

2(11,8%)

7

3(17,6%)

0

14

0

0

17

ISS(19)

18(94,7%)

1(5,3%)

0

9(47,4%)

2(10,5%)

8

10(52,6%)

1(5,3%)

8

2(10,6%)

2(10,6%)

15

3(15,8%)

0

16

HIV(10)

10(100%)

0

0

3(30%)

1(10.0%)

6

7(70.0%)

0

3

2(20.0%)

1(10.0%)

7

2(20.0%)

0

8

Non-HIV(9)

8(88,9%)

1(11,1%)

0

6(66,7%)

1(11,1%)

2

3(33,3%)

1(11,1%)

5

0

1(11,1%)

8

1(11,1%)

0

8

  1. Numbers in brackets refer to the proportion (%) of patients actually evaluated by a given diagnostic method. ICC immunocompetent, ISS immunocompromised, HIV HIV infected. HIV and non-HIV are subgroups of the ISS patients.