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Table 2 Demographic characteristics and treatment outcomes of patients with fungaemia ( N = 110)

From: Clinical characteristics and risk factors of non-Candida fungaemia

Characteristics Type of fungaemia,N(%) Pvalue
  Non-Candidafungaemia Candidaemia Overall  
  11 (10.0) 99 (90.0) 110 (100)  
Age, years a 66 (60–71) 65 (49–74) 65 (54–73) 0.80
Female gender 5 (45.5) 54 (54.5) 59 (53.6) 0.57
Hospital-acquired infection 11 (100) 95 (96.0) 106 (96.4) 0.65
Days of prior hospitalisation a, b 47 (11–66) 30 (12–60) 30 (12–60) 0.62
Admission ward at fungaemia onset 0.71
  Surgical ward 3 (27.3) 40 (40.4) 43 (39.1)  
  Medical ward 6 (54.5) 41 (41.4) 47 (42.7)  
  ICU 2 (18.2) 14 (14.1) 16 (14.5)  
Co-morbidities 11 (100) 92 (92.9) 103 (93.6) 0.47
  Solid malignancy 0 (0) 45 (45.5) 45 (40.9) < 0.01*
  Diabetes mellitus 5 (45.5) 25 (25.3) 30 (27.3) 0.14
  Gastrointestinal/hepatobiliary disease 6 (54.5) 60 (60.6) 66 (60.0) 0.47
  Chronic kidney disease 6 (54.5) 18 (18.2) 24 (21.8) 0.01*
  Haematologic malignancy 1 (9.1) 14 (14.1) 15 (13.6) 0.54
  Cardiovascular disease 3 (27.3) 17 (17.2) 20 (18.2) 0.32
  Collagen disease 3 (27.3) 9 (9.1) 12 (10.9) 0.09*
Underlying conditions
  Prior ICU admission 5 (45.5) 31 (31.3) 36 (32.7) 0.27
  Neutropaenia 1 (9.1) 7 (7.1) 8 (7.3) 0.58
  Prior bacteraemia 7 (63.6) 32 (32.3) 39 (35.5) 0.04*
  Colonisation by causative yeasts 8 (72.7) 41 (41.4) 49 (44.5) 0.05*
  Polymicrobial bacteraemia 5 (45.5) 23 (23.2) 28 (25.5) 0.11
  Assisted ventilation 2 (18.2) 17 (17.2) 19 (17.3) 0.60
  Renal replacement therapy 5 (45.5) 9 (9.1) 14 (12.7) < 0.01*
  Indwelling Foley catheter 7 (63.6) 42 (42.4) 49 (44.5) 0.15
  Central venous catheterisation 8 (72.7) 82 (82.8) 90 (8.18) 0.32
  Parenteral nutrition 8 (72.7) 80 (80.8) 88 (80.0) 0.38
  Enteral nutrition 9 (81.8) 56 (56.6) 65 (59.1) 0.09*
  Corticosteroid therapy 7 (63.6) 31 (31.3) 38 (34.5) 0.04*
  Chemotherapy 0 (0) 27 (27.3) 27 (24.5) 0.04*
  Other immunosuppressant therapy 3 (27.3) 8 (8.1) 11 (10.0) 0.08*
  Prior antibiotic therapy 10 (90.9) 89 (89.9) 99 (90.0) 0.70
  Prior antifungal therapy 4 (36.4) 18 (18.2) 22 (20.0) 0.15
  Prior surgical procedures 2 (18.2) 28 (28.3) 30 (27.3) 0.38
  Abdominal surgery 1 (9.1) 19 (19.2) 20 (18.2) 0.37
  Other surgery 1 (9.1) 10 (10.1) 11 (10.0) 0.70
SOFA score a 11 (3–17) 3 (1–9) 3.5 (1.8-10) 0.02*
Death within 30 days 6 (54.5) 21 (21.2) 27 (24.5) 0.03*
  1. ICU: intensive care unit; SOFA: sequential organ failure assessment.
  2. Data are presented as median values (interquartile range) for continuous variables and numbers of cases (%) for categorical variables.
  3. P values are marked in bold if <0.05.
  4. a Variables categorised as an ordinal scale in 1-point increments: OR > 1 is the increase in likelihood of the outcome with a 1-point increase in the factor.
  5. b Days of hospitalisation prior to fungaemia onset.
  6. * P < 0.10, variable was included in the multivariate analysis of outcomes from non-Candida fungaemia versus candidaemia.