Table 2 Demographic characteristics and treatment outcomes of patients with fungaemia ( N = 110)
From: Clinical characteristics and risk factors of non-Candida fungaemia
Characteristics | Type of fungaemia,N(%) | Pvalue | ||
|---|---|---|---|---|
Non-Candidafungaemia | Candidaemia | Overall | ||
11 (10.0) | 99 (90.0) | 110 (100) | ||
Age, years a | 66 (60–71) | 65 (49–74) | 65 (54–73) | 0.80 |
Female gender | 5 (45.5) | 54 (54.5) | 59 (53.6) | 0.57 |
Hospital-acquired infection | 11 (100) | 95 (96.0) | 106 (96.4) | 0.65 |
Days of prior hospitalisation a, b | 47 (11–66) | 30 (12–60) | 30 (12–60) | 0.62 |
Admission ward at fungaemia onset | 0.71 | |||
Surgical ward | 3 (27.3) | 40 (40.4) | 43 (39.1) | |
Medical ward | 6 (54.5) | 41 (41.4) | 47 (42.7) | |
ICU | 2 (18.2) | 14 (14.1) | 16 (14.5) | |
Co-morbidities | 11 (100) | 92 (92.9) | 103 (93.6) | 0.47 |
Solid malignancy | 0 (0) | 45 (45.5) | 45 (40.9) | < 0.01* |
Diabetes mellitus | 5 (45.5) | 25 (25.3) | 30 (27.3) | 0.14 |
Gastrointestinal/hepatobiliary disease | 6 (54.5) | 60 (60.6) | 66 (60.0) | 0.47 |
Chronic kidney disease | 6 (54.5) | 18 (18.2) | 24 (21.8) | 0.01* |
Haematologic malignancy | 1 (9.1) | 14 (14.1) | 15 (13.6) | 0.54 |
Cardiovascular disease | 3 (27.3) | 17 (17.2) | 20 (18.2) | 0.32 |
Collagen disease | 3 (27.3) | 9 (9.1) | 12 (10.9) | 0.09* |
Underlying conditions | ||||
Prior ICU admission | 5 (45.5) | 31 (31.3) | 36 (32.7) | 0.27 |
Neutropaenia | 1 (9.1) | 7 (7.1) | 8 (7.3) | 0.58 |
Prior bacteraemia | 7 (63.6) | 32 (32.3) | 39 (35.5) | 0.04* |
Colonisation by causative yeasts | 8 (72.7) | 41 (41.4) | 49 (44.5) | 0.05* |
Polymicrobial bacteraemia | 5 (45.5) | 23 (23.2) | 28 (25.5) | 0.11 |
Assisted ventilation | 2 (18.2) | 17 (17.2) | 19 (17.3) | 0.60 |
Renal replacement therapy | 5 (45.5) | 9 (9.1) | 14 (12.7) | < 0.01* |
Indwelling Foley catheter | 7 (63.6) | 42 (42.4) | 49 (44.5) | 0.15 |
Central venous catheterisation | 8 (72.7) | 82 (82.8) | 90 (8.18) | 0.32 |
Parenteral nutrition | 8 (72.7) | 80 (80.8) | 88 (80.0) | 0.38 |
Enteral nutrition | 9 (81.8) | 56 (56.6) | 65 (59.1) | 0.09* |
Corticosteroid therapy | 7 (63.6) | 31 (31.3) | 38 (34.5) | 0.04* |
Chemotherapy | 0 (0) | 27 (27.3) | 27 (24.5) | 0.04* |
Other immunosuppressant therapy | 3 (27.3) | 8 (8.1) | 11 (10.0) | 0.08* |
Prior antibiotic therapy | 10 (90.9) | 89 (89.9) | 99 (90.0) | 0.70 |
Prior antifungal therapy | 4 (36.4) | 18 (18.2) | 22 (20.0) | 0.15 |
Prior surgical procedures | 2 (18.2) | 28 (28.3) | 30 (27.3) | 0.38 |
Abdominal surgery | 1 (9.1) | 19 (19.2) | 20 (18.2) | 0.37 |
Other surgery | 1 (9.1) | 10 (10.1) | 11 (10.0) | 0.70 |
SOFA score a | 11 (3–17) | 3 (1–9) | 3.5 (1.8-10) | 0.02* |
Death within 30 days | 6 (54.5) | 21 (21.2) | 27 (24.5) | 0.03* |